Intro Flashcards
Sally needs Augmentin. She is 7 years old and weighs 66 lbs. The Augmentin dose is 80mg/kg/day. It should be given Q12 hours. It comes in a 250mg/5mL suspension. How many mL’s will you tell Mom to give per dose?
24mL Q12H
(66lbs/2.2 = 30kg. 30kg x 80mg = 2400mg per day. Divide by 2 to get 1200mg per dose. 1200mg x 5mL = \_\_\_mL x 250mg x = 24mL)
What should you always remember about pediatric dosing?
Obesity is on the rise, look out for MAX dose! Large kids might weight over 40kg, which puts them into adult dosing category. If you were to calculate by weight, then you’d overdose them.
Rule of thumb: 5mL = ____
1 tsp
Rule of thumb: 15mL = _____
1 Tbsp
Rule of thumb: 30mL = _____
1 oz
Most common infection for which abx are prescribed for children?
Otitis media
Highest risk for otitis media occurs between what ages?
6-24 months
What is the pathophysiology for OM?
Starts with rhinitis which causes swelling in nose/sinus. Swelling blocks horizontal Eustachian tube causing fluid to accumulate in the middle ear.
Lots of viruses, (such as RSV, Rhinovirus, Coronavirus, Influenza, Parainfluenza, Adenovirus, and Enterovirus) cause the majority of OM….our objectives just want us to know the 3 major bacterial causes:
1) strep pneumonia (most common)
2) H.flu (2nd most common)
3) Moraxella catarrhalis (3rd most common)
Strep pna is gram __________, H.flu is gram ________. Moraxella is gram _________.
positive, negative, negative
What are the 3 components required to make an OM dx?
1) acute onset of s/s
2) evidence of middle ear effusion
3) evidence of middle ear inflammation
erythema of TM, or generalized otalgia constitute evidence for what?
middle ear inflammation
an air-fluid level behind the TM or otorrhea are signs of what?
middle ear effusion
What is the first line tx of OM, assuming no allergies?
Amoxicillin
If Amoxicillin is not working after 2 days, what is the 2nd line tx of OM? (no allergies)
Augmentin
3rd line tx of OM? (no allergies)
3rd gen cephalosporin
What is your final resort in treating OM? (no allergies)
3rd gen cephalosporin via IM or IV
Amoxicillin specifically targets which pathogen?
strep pna
Augmentin is used when suspicion is high for which pathogens?
H.flu, M.Catarrhalis which produce beta lactamase
If the child gets a rash with PCN, what is the first line tx for OM?
3rd gen cephalosporin
If the child has an anaphylactic reaction to PCN, what is the first line tx of OM?
Clinda, Azithro, Bactrim (no effect on H.flu)
How long would you recommend these meds be given? (very general based on severity of illness)
Typical illness–5-7 days
Severe illness–10 days
IM meds–3 days
This complication of OM is characterized by scarring of the TM by hyalinization and granulation tissue deposition usually secondary to inflammation or trauma.
tympanosclerosis
This complication of OM is characterized by stratified epithelium that collects in a retracted TM (with possible eventual perforation) that can erode into the middle ear/ossicles and cause conductive hearing loss. They can even erode through the temporal bone and mastoid causing further damage and bone loss.
cholesteatoma