Intrahepatic Cholestasis of Pregnancy Flashcards
1
Q
what complication is obstetric cholestasis associated with?
A
premature birth
stillbirth
2
Q
what are the features of intrahepatic cholestasis of pregnancy?
A
- pruritus
- jaundice (~20% of patients)
- raised bilirubin
3
Q
what part of the body does pruritus typically affect in intrahepatic cholestasis of pregnancy?
A
palms, soles and abdomen
4
Q
what is the management of intrahepatic cholestasis of pregnancy?
A
- induction of labour at 37-38 weeks
- ursodeoxycholic acid
- vitamin K supplementation
5
Q
what is the rate of recurrence of intrahepatic cholestasis of pregnancy in subsequent pregnancies?
A
45-90%
