Intracellualr Accumulation And Celkular Aging

Question 1

Steosis is

Answer 1

Accumulation of fat inside cells

Question 2

Special stains used to test for lipid ( fat)

Answer 2

Oil red o
And
Sudan IV

Question 3

If the cells has lipid and Sudan IV is used

What color change shows a positive lipid present

Answer 3

Orange colour

Question 4

Fatty liver is it reversible

Answer 4

Yes

Question 5

Atherosclerosis is

Answer 5

Smooth muscle cells having a lipid vacuole filled with cholesterol

So atherosclerosis is accumution of cholesterol

Question 6

Xanthoma is what

Answer 6

Cholesterol build up in connective tissue under the skin

Characteristic of tuton gigantic cells

Question 7

Steosis usually occur in what organ

Answer 7

Liver. Majorly
Kidney tubule
Heart and skeletal muscle

Question 8

In the kidney albumin filtered by glomerular filteration is reabsorbed by

Answer 8

Pinocytosis in the proximal tubule

Question 9

Accumulation of immunoglobulin presents with what at rough endoplasmic reticulum

Answer 9

Eosinophilic Russell bodies

Question 10

Russell bodies indicate

Answer 10

An accumulation of immunoglobulin

Question 11

Mallory body is an indication of

Answer 11

Alcoholic liver disease

Question 12

Sudan IV AND OIL red o are

Answer 12

Stains used to test for lipid

Question 13

Sudan iv stains lipid what color

Answer 13

Orange

Question 14

Stains used to test for glycogen are

Answer 14

Periodic acid schiff and best carmine

Question 15

Period acid schiff is

Answer 15

A stain used to test for presence of glycogen

Question 16

Best carmine is

Answer 16

A stain used to test for glycogen presence

Question 17

Oil red o is

Answer 17

A stain used to test for lipid

Question 18

What stain color indicates the presence of glycogen

Answer 18

Rose to Violet

Question 19

Periodic acid schiff stains glycogen what color

Answer 19

Red to violet

Question 20

Dark discoloration of the lymph nodes due to carbon is

Answer 20

Anthracosis

Question 21

Accumulation of coal can cause a lung disease called

Answer 21

Coal workers pneumoconiosis

Question 22

Alkapotunuria is

Answer 22

Black urine causes by incomplete breakdown of tyrosine and phenylalanine

Question 23

Hemosiderin is accumulation of

Answer 23

Iron

Question 24

Accumulation of iron is

Answer 24

Hemosiderin

Question 25

What stain is used to test for iron

Answer 25

Prussian blue stain

Question 26

Prussian blue stain stain ——- to ——-

Answer 26

Blue to iron

Question 27

Hemosiderin is is usually occurs at what organ

Answer 27

Bone marrow
Soles
Lymph nodes

Question 28

Excess break down of heme can lead to

And why

Answer 28

Jaundice

Because
Heme breakdown causes porphyrin to be converted to bilirubin

Question 29

Jaundice is a characteristic of

Answer 29

Accumulation of bilirubin

Question 30

Dystrophic calcification is

Answer 30

Accumulation of calcium in dead cells or tissue

Serum calcium level is normal in the body in dystrophic calcification

Question 31

Metastatic calcification is

Answer 31

Accumulation of calcium in normal body tissue

Hypercalcemia is present

Question 32

Stain uses for calcium are

Answer 32

Heamotoxylin and eosin

And

Von kossa stain

Question 33

Von kossa stain stains calcium

Answer 33

Black

Question 34

Von kossa stain

Answer 34

Stain for calcium

Gives it a black deposit

Question 35

H&E stain gives calcium a

Answer 35

Basophillic granular amorphous appearance

Question 36

After a fixed number of division all cells become arrested at a phase called

Answer 36

Replicative senescence