Immunity

Question 1

What are antigen

Answer 1

Antigens are protein which when in the body cause the body to release antibody

Question 2

Hapten is

Answer 2

A small molecule that cannot elicit an antibody production

But can do it when combined with a larger protein

Question 3

Adadptive immunity consist only of

Answer 3

Lymphocyte and their product

Macrophages
Basophils e
Eosinophils
Mast cells

Question 4

Humoral immunity of the adaptive immunity is majorly controlled by

Answer 4

B lymphocyte

Question 5

Cellular immunity of the adaptive immunity is majorly controlled by

Answer 5

T lymphocyte

Question 6

Humoral immunity protect the body against ——- with what

Answer 6

Extracellular microbes with B lymphocyte

Question 7

Cellular immunity protect the body against ——- with what

Answer 7

Intracellular microbes with T lymphocyte

Question 8

Lymphoid oragan are divided into 2 namely

Answer 8

Primary or generative
Secondary

Question 9

T cells are produced from what organ

Answer 9

Thymus

Question 10

B cells are produced from what organ

Answer 10

Bone marrow

Question 11

Primary lymphoid organ includes

Answer 11

Thymus and bone marrow

Question 12

Secondary lymphoid organs include

Answer 12

Lymph nodes
MALT ( mucosa associated lymphoid tissue ) of the GIT
respiratory tract
Spleen

Question 13

In the spleen B cells and T cells are found where

Answer 13

B cells are found at red pulp
T cells are found at white pulp

Question 14

RAG 1 defeciency leads to

Answer 14

Inability to produce mature lymphocyte

Question 15

Helper T cells does

Answer 15

Stimulating the production of B cells to produce antibodies

Question 16

What constitutes 60% to 70% of the lymphoid population

Answer 16

T cells

Question 17

What constitutes 10% to 20% of the lymphoid population

Answer 17

B cells

Question 18

After B cells are stimulated by antigen they do what

Answer 18

Convert into plasma cells which produce antibodies

Question 19

Effector cells in immunity are

Answer 19

Activated lymphocyte

Question 20

Macrophages kill microbes that have been opsonized by

Answer 20

Ig G and C3B

Question 21

The dendritic cell that presents antigen to B cells are

Answer 21

Follicular dendritic cell

Question 22

The dendritic cell that presents antigen to T cells are

Answer 22

Interdigitating dendritic cells

Question 23

Follicular dendritic cells are found in

Answer 23

Lymphoid follicles

Question 24

Interdigitating dendritic cells are found

Answer 24

Under the epithelia wheee microbes enter the body

Question 25

Natural killer cells are also called

Answer 25

Large granular lymphocyte

Cause of their azurophillic granules

Question 26

Innate immunity cells include

Answer 26

Natural killers
Dendritic cells
Monocytes ( macrophages when in tissue)
Epithelia
Innate lymphoid cells

Question 27

Natural killers are part of what immunity

Answer 27

Innate immunity

Question 28

The HLA ( human leucocytes antigen )
Or MHC ( major histo compatibility complex is coded by what gene

Answer 28

Gene 6

Question 29

HLA or MHC complex presenta to what lymphocyte

Answer 29

T lymphocyte

Question 30

Class 1 MHC are found on

Answer 30

Nucleated cells and platelets

Question 31

Class 2 MHC are found on

Answer 31

Antigen presenting cells ( macrophages dendrites and B lymphocyte)

Question 32

Class 2 MHC present antigen to what type of T lymphocyte

Answer 32

CD4+ helper T lymphocyte

Question 33

Class 1 MHC present antigen to what type of T lymphocyte

Answer 33

CD8+ cytotoxic T lymphocyte

Question 34

Primary innate immunodeficiencies are
Genetically caused

Question 35

Chediak higashi syndrome is defect in

Answer 35

Forming phygolysosome

Question 36

Bruton agmmaglobinaemia is defect in

Answer 36

B cells maturation

Question 37

Bruton agmmaglobinaemia is what class of immunodeficiency

Answer 37

Primary adaptive immunodeficiency

Question 38

Di George syndrome is a defect in

Answer 38

Maturation of T cells