intervertebral disc Nucleus pulposus and annulus fibrosus Flashcards

1
Q

What is the cervical nucleus pulposus composed of

A

fibrocartilage

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2
Q

what is the water concentration in the lumbar nucleus pulposus at birth and after 30

A

birth 88%

thrity 70%

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3
Q

What is the consequence of non-aggregated glycosaminoglycans in the lumbar nucleus pulposus

A

the nucleus pulposus will loose water under deformation conditions

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4
Q

What cell is associated with the nucleus pulposus until about age 11

A

notochord cells

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5
Q

what cells are associated with the mature nucleus pulposus

A

collagen type 2

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6
Q

what general tissue location is described as having an abundance of collagen type 2 fibers

A

cartilage

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7
Q

what is the role of collage type 2 fibers based on locations where it is dominant

A

it appears to be related to tissues having a deformation-reformation ability

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8
Q

What is the appearance of the cervical annulus fibrosus

A

a horse-shoe with the anterior margin thick and the lateral margins tapering to the uncinate processes; the posterior margin is thin

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9
Q

What compensates for the thinness of the posterior part of the cervical annulus fibrosus

A

posterior longitudinal ligament

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10
Q

what is the organization of the lumbar annulus fibrosus

A

it has 12-14 concentric cylindrical lamellae

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11
Q

what is the water concentration in the lumbar annulus fibrosus at birth and after 30

A

birth 78%

thirty 70%

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12
Q

what is the organizational pattern for glycosaminoglycans in the lumbar annulus fibrosus

A

they typically have a binding site for hyaluronic acid and are thus aggragated

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13
Q

which type of collagen is dominant in the annulus fibrosus

A

collagen type 1

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14
Q

what is the organizational pattern for collagen fibers in the annulus fibrosus

A

they are parallel with one another in a single lamellus and angled

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15
Q

what is the organization of collagen fibers between lamellae

A

collagen fibers will be angled in the opposite direction such that a spiral counterspiral organization is observed

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16
Q

what is the average angle of collagen fibers within the annulus fibrosus

A

they average 50-60 degrees

17
Q

what is the origin for the cells of the annulus fibrosus

A

sclerotomites