Interstitial Lung Disease Flashcards

1
Q

Interstitial Lung Disease

A

Any disease affecting lung interstitium
Interferes with gas transfer
Restrictive lung pattern

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2
Q

Symptoms of InterstitIal Lung Disease

A

Breathlessness

Dry cough

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3
Q

Biopsies

A

Transbronchial

Thorascopic

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4
Q

Sacroidosis

A

Type 4
Granulomatous
Non-caseating granuloma of unknown aetiology
Less common in smokers

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5
Q

Sarcoidosis Incidence

A

10-20/100,000

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6
Q

Commonly affected areas with sarcoidosis

A

Lungs, lymph nodes, joints, liver, skin, eyes

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7
Q

Less common affected areas by sarcoidosis

A

Kidneys, brain, nerves heart

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8
Q

Acute Sarcoidosis

A
Erythema Nodosum
Bilateral Hilar Lymphadenopathy
Arthritis
Uveitis, partotits
Fever
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9
Q

Chronic Sarcoidosis

A

Lung infiltrates
Skin Infliltrates
Peripheral lymphadenopathy
Hypercalcaemia

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10
Q

Sarcoidosis Investigations

A
CXR - Bilateral Hilar Lymphadenopathy
CT - peripheral nodular infiltrate
Tissue Biopsy
Pulmonary function test (Restrictive)
Blood test (ACE, Ca+, inflammatory markers)
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11
Q

Treatment of acute sarcoidosis

A

None

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12
Q

Treatment of chronic sarcoidosis

A

Oral steroids needed

Immunosupression

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13
Q

Hypersensitivity Pneumonitis

A

Type III

Reaction to antigen lymphocytic alveolitis

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14
Q

Acute Hypersensitivity Pneumonitis

A

Cough, breathlessness, fever, myalgia
Pyrexia, crackles, hypoxia
CXR = wide spread pulmonary inflitrates

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15
Q

Treatment of acute hypersensitivity pneumonitis

A

Oxygen, steroid and antigen avoidance

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16
Q

Chronic Hypersensitivity Pneumonitis

A
Repeated low dose exposure over time
Progressive breathlessness and cough
Crackles
CXR = Pulmonary Fibrosis
Pulmonary Function = restrictive
17
Q

Treatment of Chronic Hypersensitivity Pneumonitis

A

Remove antigen exposure

Oral steroids if breathless or low gras transfer

18
Q

Idiopathic Pulmonary Fibrosis

A
Most common interstitial lung disease
Progressive breathlessness, dry cough
Clubbing, bilateral fine inspiratory crackles
CXR = bilateral infiltrates
CT = reticulondular fibrotic shadowing
19
Q

Simple Pneumoconiosis

A

CXR abnormality only

No impairment of lung function

20
Q

Complicated pneumoconiosis

A

Progressive massive fibrosis (restrictive)

21
Q

Caplans syndrome

A

Rheumatoid pneumoconiosis

22
Q

Silicosis

A

15-20 years exposure to Quartz

CXR = egg shell calcification of hilar nodes

23
Q

Asbestos

A

Mining, construction
Pleural disease:
1. Benign pleural plaques - asymptomatic
2. Acute asbestos pleuritis - fever, pain, bloody pleural effusion
3. Pleural Effusion and Diffuse Pleural Thickening - restrictive impairment
4. Malignant mesothelioma - fatal