Interstitial and fibrotic lung disease Flashcards
Intersitial lung disease encompasses which disease?
Extrinsic allergic alveolitis
Idiopathic pulmonary fibrosis
Industrial lung diease- Asbestosis
What is the pattern on spirometry of interstitial lung disease?
restrictive
Three causes of interstitial lung disease?
asbestos, silicon Drugs Hypersensitivity Infection- TB, viral, fungi IDIOPATHIC
Name two drugs associated with interstitial lung disease
methotrexate
amiodarone
nitrofurantoin
sulfasalzine
Name a condition in which pulmonary fibrosis can occur as a secondary consequence
RA
SLE
Sarcoidosis
Alpha1 antitrypsin deficiency
Two specific causses of extrinsic allergic alveolitis/ hypersensitivity pneumonitis?
Bird fancier’s lung- bird dropping
Farmer’s lung- mouldy spores in hay
Mushroom worker’s lung
Malt worker’s lung- aspergillus
Two investigations for intersitial lung disease?
HRCT Lung biopsy CXR Spirometry Bloods
What is a seminal feature of interstitial lung disease on HRCT?
ground glass appearance
What is the most common causes of intersitial lung disease?
idopathic pulmonary fibrosis
Which specific feature of intersitial lung disease can you see on CXR?
honeycombing
What is the cure for idiopathic pulmonary fibrosis?
lung transplant
Provide a brief description of the pathophysiology of interstitial lung disease
fibrosis and inflammation of the lung parenchyma