Internal Anatomy of the Brainstem 2 Flashcards

1
Q

What is the function of the inferior cerebellar peduncle?

A

Input pathway to the cerebellum for most ascending somatosensory infromation and from the inferior olive

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2
Q

What is the middle cerebellar peduncle?

A

Pathways for input to the cerebellum from the pontine nuclei in the basal pons

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3
Q

What is the superior cerebellar peduncle?

A

Major output pathway from the cerebellum to the midbrain and thalamus

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4
Q

What is the dorsal spinocerebellar tract?

A

Conveys unconscious proprioception from the lower limbes and trunk

Primary axons ascend in the gracile fasiculus and synapse in Clark’s nucleus

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5
Q

What is the cuneocerebellar tract?

A

Conveys uncsonscious proprioception from the upper limbs and trunk

Entirely ipsilateral, synapses in accessory cuneate nucleus

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6
Q

What is the ventral spinocerebellar tract?

A

Originates in interneurons in the intermediate zone of spinal cord grey matter

Decussates twice

Conveys information about movements of the lower limb and trunk, and adjustments in posture

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7
Q

What is the olivocerebellar pathway?

A

Inferior olivary nucleus neurons project to cerebellum through the inferior cerebellar peduncles

Important functions in motor learning

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8
Q

What is the vestibulocerebellar pathway?

A

Includes both primary vestibular afferents and the axons of secondary vestibular neurons

Provides vestibular information to the cerebellum through a portion of the inferior cerebellar peduncles called the juxtarestiform body

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9
Q

What is the corticopontocerebellar pathway?

A

Fibers from the cortex synapse in the ipsilateral pontine nuclei

Pontocerebellar fibers cross and enter the contralateral middle cerebellar peduncle

Pathway provides cerevellum with information about all the various sensations affecting the body and planned and ongoing movement

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10
Q

Where does output from the cerebellum go?

A

Through the superior cerebellar peduncles

Exception is some vestibular output

Decussate at the level of the inferior colliculi and project to the contralateral red nucleus and ventrolateral nucleus of the thalamus

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11
Q

What four symptoms result from lesions of the cerebellar peduncles?

A

Ataxia

Dysmetria

Vertigo

Nausea

Similar to cerebellar lesions

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12
Q

Where do afferents from taste-sensing CNs (VII, IX, X) project?

A

Rostral portion of the solitary nucleus

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13
Q

What is the pathway that mediates conscious taste sensation?

A

Ascending pathway from the solitary nucleus to the ventral posterior medial nucleus of the thalamus, and from there to the primary gustatory cortex

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14
Q

Where is the primary taste cortex?

A

Insula and frontal operculum of the cerebral hemispheres

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15
Q

What are saccades?

A

Very rapid, voluntary eye movements that serve to direct vision to objects of interest

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16
Q

What is smooth pursuit?

A

Rapid, non-voluntary eye movement that acts to stabilize vision of moving objects

17
Q

What is vergence?

A

Simultaneous adduction of both eyes

Slower eye movement which allows maintained vision for objects moving towards or away from the body

18
Q

Why does the abducens nucleus function as a control center for horizontal gaze?

A

The abducens contains LMNs for the lateral rectus and neurons that project to the contralateral oculomotor nucleus in order to activate the contralateral medial rectus

19
Q

What is the paramedian pontine reticular formation?

A

Receives input for higher level eye movement control centers

Projects to the ipsilateral abducens nucleus and “programs” appropriate activity for conjugate horizontal gaze

20
Q

What is the result of a lesion to the abducens nerve?

A

Impaired abduction of the ipsilateral eye

21
Q

What results from a lesion to the abducens nucleus?

A

Ipsilateral gaze palsy

Both eyes affected

E.g. right abducens nucleus lesion prevents rightward gaze of both eyes

22
Q

What results from a lesion in the paramedian pontine reticular formation?

A

Ipsilateral gaze palsy

Both eyes affected

23
Q

What is Intranuclear ophthalmoplegia?

A

Lesion in the medial longitudinal fasciculus

Causes failure of adduction in the ipsilateral eye

Abduction in the contralateral eye is accompanied by nystagmus

24
Q

What results from a lesion in the abducens nucleus or PPRF and the medial longitudinal fasciculus?

A

Ipsilateral gaze palsy AND intranuclear ophthalmoplegia

Ipsilateral eye loses all horizontal movement

Contralateral eye can only abduct

25
Q

What types of lesions may affect upward gaze? Downward?

A

Upward - Dorsal midbrain (e.g. pineal tumors and hydrocephalus

Downward - Ventral midbrain

26
Q

What are the frontal eye fields and where do they project?

A

Brodmann area 8

Projects to the contralateral PPRF

27
Q

What is the result of a lesion in one of the frontal eye fields?

A

Gaze preference towards the side of the lesion

*Intact side directs gaze towards the lesioned (contralateral) side

28
Q

What is the function of the parietal-occipital-temporal area?

A

Directs smooth pursuit eye movements in an ipsilateral direction

29
Q

What is the function of the caudal solitary nucleus?

A

Recievves visceral sensory input from chemoreceptors about blood oxygen and pH

Important for respiration

30
Q

What is the function of the pre-Botzinger complex?

A

Located in the ventro-lateral medullary reticular formation

Acts as a major pacemaker center for respiration