INTERLEUKINS Flashcards
T cell growth factor
_Interleukin-2 (IL-2)
Lymphocyte-activating factor
Interleukin-1 (IL-1)
B cell growth factor 2
Interleukin-5 (IL-5)
Multicolony colony-stimulating factor
Interleukin-3 (IL-3)
NK cell stimulatory factor
Interleukin-12 (IL-12)
Stimulates neutrophils in chemotaxis
Interleukin-8 (IL-8)
Induce acute phase response
Interleukin-6 (IL-6)
Stimulates expansion of immature T and B cells
Interleukin-7 (IL-7)
Enhances cytolytic activity of lymphokine-activated killer cells (LAK)
Interleukin-2 (IL-2)
Potent mediator in acute-phase response
Interleukin-1 (IL-1)
Stimulates hematopoietic cells
Interleukin-3 (IL-3)
Enhances production of IgG and inhibits production of IgE by activated B cells
Interleukin-4 (IL-4)
Induction of secretion of Ig
Interleukin-6 (IL-6)
Activates the respiratory burst
Interleukin-8 (IL-8)
Stimulates early B cell progenitor cells
Interleukin-7 (IL-7)
Activates eosinophils
Interleukin-5 (IL-5)
Inhibits cytokine synthesis
Interleukin-10 (IL-10)
Increases the number of IgG-secreting B lymphocytes
Interleukin-11 (IL-11)
Stimulates proliferation of T cells and mast cells
Interleukin-9 (IL-9)
Enhances the activity of cytotoxic effector T cells
Interleukin-12 (IL-12)
Inhibits activation of macrophages
Interleukin-13 (IL-13)
Produced in response to viral infection
Interleukin-15 (IL-15)
Acts as a T cell chemoattractant
Interleukin-16 (IL-16}
Acts as a B cell growth factor
Interleukin-14 (IL-14)
Acts as a synergist with IL-12
Interleukin-18 (IL-18)
Suppresses activities of Th1 and Th2
Interleukin-19 (IL-19)
Associated with skin inflammations
Interleukin-20 (IL-20)
Induces granulopoiesis
Interleukin-17 (IL-17)
. Promotes increased production of T cells
Interleukin-21 (IL-21)
Somewhat similar to IFN-α, IFN-β, and IFN-γ
Interleukin-22 (IL_22)
A member of the IL-17 cytokine family
Interleukin-25 (IL-25)
Shares some in vivo functions with IL-12
Interleukin-23 (IL-23)
