The lymphoid system

Question 1

Which of the following is a primary lymphoid organ?

a. Lymph node
b. Spleen
c. Thymus
d. MALT

Answer 1

c. Thymus

Question 2

What type of cells would be found in a primary follicle?

a. Unstimulated B cells
b. Germinal centers
c. Plasma cells
d. Memory cells

Answer 2

a. Unstimulated B cells

Question 3

Which of the following is true of NK cells?
a. They rely on memory for antigen recognition.
b. They share antigens with B cells.
c. They are found mainly in lymph nodes.
d. They recognize a lack of MHC proteins.

Answer 3

d. They recognize a lack of MHC proteins

Question 4

Where are all undifferentiated lymphocytes made?

a. Bone marrow
b. Thymus
c. Spleen
d. Lymph nodes

Answer 4

a. Bone marrow

Question 5

in the thymus, positive selection of immature T cells is based upon recognition of which of the following?

a. Self-antigens
b. Stress proteins
c. MHC antigens
d. μ chains

Answer 5

c. MHC antigens

Question 6

Which of these are found on a mature B cell?

a. IgG and IgD
b. IgM and IgD
c. Alpha and beta chains
d. CD3

Answer 6

b. IgM and IgD

Question 7

Which receptor on T cells is responsible for rosetting with sheep red blood cells?

a. CD2
b. CD3
c. CD4
d. CD8

Answer 7

a. CD2

Question 8

Which of the following can be attributed to antigen-stimulated T cells?

a. Humoral response
b. Plasma cells
c. Cytokines
d. Antibody

Answer 8

c. Cytokines

Question 9

Which is a distinguishing feature of a pre-B cell?
a. μ chains in the cytoplasm
b. Complete IgM on the surface
c. Presence of CD21 antigen
d. Presence of CD25 antigen

Answer 9

a. μ chains in the cytoplasm

Question 10

When does genetic rearrangement for coding of light chains take place?

a. Before the pre-B cell stage
b. As the cell becomes an immature B cell
c. Not until the cell becomes a mature B cell
d. When the B cell becomes a plasma cell

Answer 10

b. As the cell becomes an immature B cell

Question 11

Which of the following antigens are found on the T cell subset known as helper/inducers?
a. CD3
b CD4
c. CD8
d. CD11

Answer 11

b CD4

Question 12

Where does the major portion of antibody production occur?
a. Peripheral blood
b. Bone marrow
c. Thymus
d. Lymph nodes

Answer 12

d. Lymph nodes

Question 13

Which of the following would represent a double-negative thymocyte?
a. CD2–CD3+CD4–CD8+
b. CD2+CD3–CD4–CD8–
c. CD2–CD3+CD4+CD8–
d. CD2+CD3+CD4+CD8–

Answer 13

b. CD2+CD3–CD4–CD8–

Question 14

Which of the following best describes the T-cell receptor for antigen?

a. It consists of IgM and IgD molecules.
b. It is the same for all T cells.
c. It is present in the double-negative stage.
d. Alpha and beta chains are unique for each antigen.

Answer 14

d. Alpha and beta chains are unique for each antigen