interleukins

Question 1

IL-1

Answer 1

macrophages. induces fever

Question 2

IL-2

Answer 2

TH1 cells. stimulates growth and differentiation of T cell response

Question 3

IL-3

Answer 3

Activated T helper cells. stimulates differentiation and proliferation of myeloid progenitor cells

Question 4

IL-4

Answer 4

TH2 cells. proliferation and differentiation of B cells

Question 5

IL-5

Answer 5

TH2 cells. stimulate production of eosinophils

Question 6

IL-6

Answer 6

macrophages, TH2 cells. differentiation of B cells. induces fever

Question 7

IL-8

Answer 7

macrophages. neutrophil chemotaxis

Question 8

IL-10

Answer 8

TH2 cells. inhibits Th1 cytokine production. anti inflammatory cytokine

Question 9

IL-12

Answer 9

dendritic cells. macrophages, B cells. Activates Nk cells

Question 10

IgG

Answer 10

most abundant, crosses into foetal circulation. enhances phagocytosis. (monomer)

Question 11

IgA

Answer 11

most commonly produces in body. breast milk (Dimer) provides protection on mucous membranes

Question 12

IgM

Answer 12

first secreted in response to infection. doesnt cross into foetal circulation (Pentamer)

Question 13

IgE

Answer 13

expressed by mast cells and basophils. mediates type 1 hypersensitivity, asthma, allergy, parasites. least abundant (monomer)

Question 14

IgD

Answer 14

mediated B lymphocyte activation (monomer)

Question 15

what is allergic asthma mediated by

Answer 15

TH2 cells

Question 16

what do B cells do

Answer 16

antibody production

Question 17

MHC class 1 molecules

Answer 17

bind w CD8 receptors on cytotoxic T cells

Question 18

MHC class II molecules

Answer 18

bind w CD4 receptors on T helper cells