Interleukins Flashcards

1
Q

IL-1 Source

A

Macrophage
Lymphocytes
endothelium
fibroblasts
astrocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

IL 1 target cell

A

T cells
B cells
macrophages
endothelium
tissue cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

IL- 1 effect

A

Lymphocyte activation
leukocyte endothelial adhesion
fever
regulates sleep

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

IL 2 source

A

T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

IL 2 target cell

A

T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

IL 2 effect

A

T cell growth factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

IL 3 source

A

T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

IL 3 target

A

bone marrow cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

IL 3 function

A

stimulates bone marrow growth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

IL 4 source

A

T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

IL 4 target

A

B and T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

IL 4 effect

A

B cell growth factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

IL 5 source

A

T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

IL 5 target

A

B cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

IL 5 effect

A

B cell growth factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

IL 6 source

A

T and B cells
macrophages
fibroblasts

17
Q

IL 6 target cells

A

B cells and hepatocytes

18
Q

IL 6 effect

A

B cell differentiation and synthesis of acute phase reactants

19
Q

IL 7 source

A

lymphocytes

20
Q

IL 7 target

A

B and T cells

21
Q

IL 7 stimulates proliferation of immature cells

A
22
Q

IL 8 source

A

T cells
macrophages

23
Q

IL 8 target

A

granulocytes
endothelium

24
Q

IL 8 effect

A

stimulates the activity of neutrophils
acts as chemotaxin
inhibitor of endothelial cell leukocyte adhesion

25
Q

IL 9 source

A

T cells

26
Q

IL 9 target

A

T cells

27
Q

IL 9 effect

A

T cell and mast cell growth enhancement

28
Q

IL 10 source

A

T cells

29
Q

IL 10 target

A

macrophage

30
Q

IL 10 effect

A

suppresses development of T cells subpopulations by inhibition of macrophage IL 12 production

31
Q

IL 11 source

A

bone marrow stromal cells

32
Q

IL 11 target

A

hepatocytes

33
Q

IL 11 effect

A

induces synthesis of acute phase proteins

34
Q

IL 12 source

A

macrophage

35
Q

IL 12 target

A

T cells

36
Q

IL 12 effect

A

enhances B cells expression of IFN-y during T cell activation
stimulates lymphocyte subpopulation (NK cells)