Intergration of Synaptic Potentials and Introduction to Neural Networks Flashcards
What are synaptic potentials?
they are the transmission of electrical potential from presynaptic nerve terminals to the postsynaptic neuronal dendrite
What are the steps in the mechanism of synaptic potentials?
1) neurotransmitter remains in vesicle
2) neurotransmitter diffuses across synaptic cleft
3) neurotransmitters open voltage gated ion channels so Na+ diffuses down the concentration gradient causes depolarisation
4) synaptic potential declines as neurotransmitter molecules unbind
5) total decay of synaptic potential
What does the amplitude of post synaptic potentials depend on?
amount of neurotransmitter released
number or receptors
state of receptors
What does decay of post-synaptic potentials depend on?
Dissociation of ligand
diffusion and uptake
desensitisation
enzymatic destruction
What are IPSP’s?
inhibitory postsynaptic potentials prevent somatic depolarisation and generation of action potential
Stages on convergence of neuronal pathways?
1) Shock artefact
2) Synaptic delay
3) EPSP due to opening of ligand gated cation channels
4) action potential due to voltage gated Na+ channels
5) hyperpolarising after potential die to VG K+ channels
6) IPSP due to opening of ligand gated anion channels
What is acuity?
acuity is the clearness and sharpness of a sensory function