Blood - CNS Barriers

Question 1

what are the 7 main vascular components supplying the brain?

Answer 1

carotid arteries
vertebral arteries
pial arteries
penetrating arteries
penetrating arterioles
intracerebral arterioles
capillaries

Question 2

What are pericytes?

Answer 2

Immune function to trap macromolecules on the way to brain interstitial fluid

Question 3

Whats the main function of astrocytes?

Answer 3

to maintain the blood brain barrier

Question 4

How do substances move past the blood brain barrier?

Answer 4

Simple diffusion through paracellular cleft

passive diffusion of molecule through plasma membrane of luminal and abluminal membrane

Question 5

Features of cerebral capillary endothelium?

Answer 5

physical barrier
transport/selective barrier
metabolic barrier

Question 6

What are the functions of the blood brain barrier?

Answer 6

controls molecule influx into brain interstitial fluid
supplies brains with essential nutrients
mediates efflux of waste products
restricts ionic and fluid movements