Interactions (selected) Flashcards

1
Q

ACEinhibitors (2)

A

Lithium

Allopurinol

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2
Q

Eplerenone (1) + nature of reaction

A

Azole antifungals - increased exposure

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3
Q

Which type of diuretics is best avoided on Aminoglycosides?

A

Loop diuretics

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4
Q

Aminophylline/Theophylline (4)

A

Smoking
St Johns Wort

CoC
b-blockers

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5
Q

Amiodarone (4)

A

Grapefruit juice
b-blockers
Warfarin
Diltiazem & Verapamil

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6
Q

Carbamazepine (3)

A

Azoles
Clozapine
Rivaroxaban

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7
Q

Anti-epileptics (2)

A

CoC

CCBs (verapamil & diltiazem)

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8
Q

b-blockers (3)

A

Amiodarone
Theophylline/Aminophylline
Verapamil/Diltiazem

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9
Q

Clopidogrel (4)

A

Azoles
Grapefruit juice
Omeprazole
Fluoxetine

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10
Q

Clozapine (4)

A

CoC
Carbamazepine
Erythromycin
Ciprofloxacin

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11
Q

Colchicine (1)

A

Macrolides

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12
Q

Steroids (2)

A

NSAIDs

Clarithromycin

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13
Q

Warfarin (3)

A

Grapefruit&cranberry juice
Miconazole
Amiodarone

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14
Q

Anti-psychotics (1)

A

Parkinson`s drugs - antagonising action

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15
Q

Fibrates (1)

A

Colchicine - risk of rhabdo

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16
Q

Fusidic acid (1)

A

Statins - avoid

17
Q

Lithium

A

NSAIDs
ACEis/ARBs
Loop & Thiazide diuretics

18
Q

Methotrexate (5)

A
High-dose aspirin
NSAIDs
Penicillins
Trimethoprim
High dose PPIs
19
Q

NSAIDs (4)

A

Lithium
Methotrexate
Steroids
Bisphosphonates

20
Q

Retinoids (1)

A

Vitamin A

21
Q

Adrenaline and co (1)

A

b-blockers - increased risk of HTN and bradycardia

22
Q

Tetracyclines (1)

A

Retinoids

23
Q

Vit D preps (1)

A

Digoxin - increased risk of toxicity