Blood & Nutrition

Question 1

Which drugs have a definite risk of haemolytic anaemia in G6PD deficiency?

Answer 1

Dapsones, Hydroquinolones, Methylthioninium chloride, Nitrofurantoin, Sulphonamides

Question 2

Why are MR preps of oral iron not recommended?

Answer 2

Very poor oral bioavailability

Question 3

When would you start oral iron after iron injection?

Answer 3

After at least 5 days

Question 4

Side-effects of oral iron

Answer 4

GI side-effects, Constipation that can lead to faecal impaction, stool discolouration

Question 5

When would you stop oral iron after iron lvls returned to normal?

Answer 5

Continue for 3 months after lvls in range

Question 6

How long is the course of folic acid in folate deficiency?

Answer 6

4 months

Question 7

Iron overload treatment

Answer 7

Desferrioxamine

Question 8

Nitropenia rescue drug

Answer 8

Filgrastim

Question 9

Main risks of Filgrastim (2)

Answer 9

Acute respiratory distress syndrome

Splenomegaly & spleen rupture

Question 10

Acute hyperkalaemia management

Answer 10

Ca gluconate 10%
Soluble insulin (5-10 units) + 50mg of 50% glucose
Nebulised salbutamol - use with caution

Question 11

First line in severe hypercalcaemia

Answer 11

Pamidronate sodium

Question 12

When is Cinacalcet used

Answer 12

Secondary hyperparathyroidism

Question 13

When is Calcitonin used

Answer 13

Hypercalcaemia associated with malignancy

Question 14

Common side-effect of phosphate supplements

Answer 14

Diarrhoea

Question 15

Which excipient should be avoided in people with phenylketonuria?

Answer 15

Aspartame

Question 16

Which foods should be avoided in people with phenylketonuria?

Answer 16

Dairy, eggs, meat

Question 17

Which vitamins are water-soluble

Answer 17

B & C

Question 18

Which vit D deficiency medication should be used in renal impairment

Answer 18

Alfacalcidol