Integumentary Exam #1 Flashcards
What is the primary function of skin?
surface barrier against invading organisms
What are 8 other functions of skin?
- Homeostasis
- Thermoregulation
- Sensory Perception
- Excretion
- Skin lubrication
- Synthesis of vitamin D
- Absorption of medications
- Personal Identity
What are the 3 layers of skin?
- Epidermis
- Dermis
- Subcutaneous
What is the outermost layer of skin?
Epidermis (very thin)
How often does the epidermis regenerate?
Every 28 days
How is the epidermis nourished?
By blood vessels in the dermis bc it is avascular
What are the 2 types of epidermal cells?
Keratinocytes & Melanocytes
What is the function of keratinocytes?
produce keratin which serves as a protective barrier
What is the function of Melanocytes?
secrete melanin, which gives skin/hair color & provides UV protection
What are the 2 layers of the dermis?
Papillary layer & Reticular layer
What is the papillary layer of the dermis?
upper, thin layer, made up of ridges which form finger/foot prints
What is the reticular layer of the dermis layer?
lower, thicker layer, provides support (collagen, elastin & reticular fibers)
What is the SubQ layer?
layer of connective tissue that attaches skin to underlying tissue & organs
What is the primary function of the SubQ layer?
insulation
What are hair & nails made of?
dead keratin cells
What is the matrix of the nail?
white crescent shaped area at base of nail
What are 3 types of glands?
- Sebaceous
- Apocrine
- Eccrine
What is the function of sebaceous glands?
secrete sebum (oil) to keep skin & hair from becoming too dry
What are Apocrine glands?
sweat glands that smell bad (i.e. in armpits/groin) Apocrine = Adolescence
What are Eccrine glands?
sweat glands that cool by evaporation. Eccrine = exercise
Why does hair turn white or grey when people age?
b/c of decrease in melanin
What are lentigo?
sun spots/ liver spots
What are 4 types of photosensitizing drugs?
sulfa, diuretics, tetracycline, doxycycline
What is the difference between an allergy & an irritation?
allergies are immunological responses that happen consistently with exposure to same antigen
irritations = unpredictable!
What regulates eccrine sweat glands?
Adrenergic nervous system (exercise, heat, emotional stress, fever)
What causes wrinkles/sagging in elderly?
decrease in subQ fat, degeneration of elastic fibers, collagen stiffening
What causes dry/flaky skin in elderly?
decreased activity of apocrine & sebaceous gland activity
What are S/E of diminished blood supply?
decreased sensation & wound healing
Which 3 things affect skin color?
melanin, carotene & hemoglobin
Where are the most reliable areas of least pigmentation to inspect for color changes?
sclera, conjunctiva, nail beds, lips, buccal mucosa
Vascularity: blanchable=?
due to dilated blood vessels
vascularity: not blanchable=?
due to subQ or intradermal bleed
What 5 things is it important to document in regard to lesions?
- size
- location
- color
- distribution
- shape
What is a primary lesion?
lesions which appear on previously healthy skin in response to irritation
What is a secondary lesion?
lesions which result from changes in primary lesion
What are bulla?
fluid filled lesions 0.5-2cm AKA blisters (large vesicles)
What are cysts?
semisolid or fluid filled encapsulated mass extending deep into dermis ie acne
What are macules?
FLAT, pigmented, circumscribed <0.5 cm (ie a freckle)
What is a papule?
a firm, inflammatory, RAISED lesion that is less than 0.5 cm
What is a nodule?
a firm, raised, inflammatory lesion that extends deeper than a papule, into all 3 skin layers 0.5-2cm
What is a pustule?
a lesion containing purulent material
What is a vesicle?
a serous-fluid filled lesion less than 0.5 cm (small blister)
What is a wheal?
raised, firm lesion with intense localized skin edema (AKA hives) ITCHY
What causes a keloid scar?
hyperplasia of fibrous tissue
What is vitiligo?
disappearance of skin’s melanocytes