Integumentary Flashcards
What is the general purpose of the epidermis?
Outer most layer (only a max. Of 1.5mm thick)
Protects deeper layers from mechanical, thermal and chemical damage
Protects from pathogen and UV radiation
What are the main layers of the epidermis from superficial to deep?
Stratum corneum
Stratum granulosum
Stratum spinosum
Stratum basale
What is the stratum corneum?
Outer most layer of epidermis
Comprised of dead skin cells that continually shed and are replaced
Provides waterproofing
What is the stratum granulosum?
The second deepest epidermal layer
Comprised of granula cells which provide keratin
Gives structure and integrity
What is the stratum spinosum?
Between the granulosum and basale epidermal layers
Has several layers of cells that give support and strength
What is the stratum basale?
Deepest epidermal layer
New skin cells (keratinocytes) made here. Undergo keratinisation where they are hardened and pushed up as more new cells are produced
Melanocytes produce melanin
What produces skin tone variation?
The ratio of the different forms of melanin in the stratum basale
What is the purpose of keratin in skin?
Helps with fluid retention
Healing and repair
Gives shape and structure
Describe the dermis
Thick middle layer of skin
Has two layers: superficial papillary dermis and deep reticular dermis
Many capillary networks to provide oxygen and nutrients
Collagen and elastin provide shape and elasticity
Hair follicles, glands, erector pili muscles and nerve endings
Describe the hypodermis
Also called subcutaneous tissue (means tissue under the skin)
Comprised of loose connective tissue and adipose tissue
Connects skin to muscle, maintains temperature, adipose stores glucose that can be used for energy and helps with protection
What causes acne?
Hair follicle gets clogged with oil and dead skin cells
Influenced by high oil levels, hormones, genetics, bacteria and inflammation
What are the symptoms of acne?
Usually on face, black, chest and shoulders
Presents as whitehead, blackhead, pustule, cyst
What is the treatment for acne?
Refer to dermatologist or GP
Topical benzoyl peroxide or salicylic acid
Oral hormone, AB or isotretinoin
What causes psoriasis?
A chronic autoimmune disease causes mass skin cell production that accumulates on surface of skin
What are the symptoms of psoriasis?
Commonly on elbows, knees, scalp and back
Thick silver scales/red patches
Flares up when stressed, infection, injury, weather changes, some medication
What is the treatment for psoriasis?
Refer to dermatologist/GP
Topical and oral medication, light therapy
What is skin cancer?
Abnormal cell growth due to damaged cell DNA
Usually caused by prolonged UV radiation exposure
Can be BCC is stratum basale, SCC in keratinocytes or melanoma in melanocytes
What is the treatment for skin cancer?
Refer to dermatologist/GP
Needs a biopsy
Medication, radiation therapy or excision
How does the body produce and retain its own heat?
Heat is produced as a by product of metabolic processes
Skin helps to retain this heat, especially adipose tissue
What might cause the body to overheat?
Illness, exertion, hot environment, medication
How does the body thermoregulate when too hot?
Dilates capillary beds in the skin so more heat can be transferred out
Sweat is produced (salt and water fro eccrine glands in dermis). It is released onto the skin where heat is transferred into it and then gets evaporated off the body
Negative feedback loop
How does the body thermoregulate when too cold?
Constricts capillary networks in the skin so less heat is transferred out.
Activates erector pili muscles in the dermis to cause shivering - metabolic processes produce heat
Negative feedback loop
What is an apocrine gland?
Located in armpits and genital areas
Activated at puberty - hormone triggered
Responsible for body odour and pheromones
Specialised forms exist e.g. glands in ear makes earwax, ciliary gland in eye controls tears, mammary helps with milk production
What are eccrine glands?
Activate at birth
Produce sweat