Integument And Immune Flashcards

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0
Q

The ___ contains the blood supply to the skin and the specialized cells whereas the ____ contains keratinocytesp

A

Dermis

Epidermis

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1
Q

Secrete oil onto the surface of the skin to keep its pH relatively acidic and decreases bacterial growth

A

Sebaceous glands

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2
Q

Keratinocytes differentiate into ___ : waterproof cells often replaced and sloughed off

A

Corneocytes

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3
Q

2 major types of immunity ?

A

Humoral: antibody production

Cell-mediated : cells combatting fungal and viral infections

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4
Q

The released chemical from white blood cells activating the immune system

A

Histamine

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5
Q

Histamine function?

A

Dilates and increases the permeability of blood vessels

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6
Q

Kills temperature dependent pathogens and speeds up the healing process

A

Fever

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7
Q

Reservoirs of white blood cells and filters for lymph, removing antigen presenting cells and foreign matter and activating the immune system when necessary

A

Lymph nodes and spleen

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8
Q
First responders
Attracted to cytokines 
Attract WBC
Attack bacteria 
Main component of pus
A

Neutrophils

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9
Q
Immune responses 
Less common
Allergic/asthmatic responses 
React to ectoparasites
Related to mast cells 
Histamine
Heparin
A

Basophils

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10
Q

Parasites living on the surface of skin such as fleas and ticks. Trigger allergic reactions

A

Ectoparasites

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11
Q
Release histamine 
Stimulate blood vessel dilation 
Indicate Helminths (intercellular parasitic worms )
Allergic responses 
Phagocytes
A

Eosinophils

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12
Q

Large long lived immune cells that can differentiate into macrophages and dendritic cells

A

Monocytes

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13
Q

Phagocytize dead cells and pathogens. Antigens of ingested pathogens are presented On outside to mount a specific immune response

A

Macrophages

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14
Q

More focused on processing antigens and presenting them to other immune cells.found where contact with external environment is common

A

Dendritic cells

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15
Q

Specific immunity. Becomes reactive to only one random antigen type, presented by a major histocompatibility protein complex. Enough created to defend body against nearly any pathogen

A

T cells

16
Q

Cytotoxic T cells. (Cd8 + T cells )
Respond to?
Function ?

A

MHC I
Cells infected with viruses or developing tumors

Destroy these cells

17
Q

T helper cells (cd4+)
Respond to?
Function?

A

MHC II

Released cytokines and stimulate immune response

18
Q

Natural killer T cells

Respond to?

A

Other antigens present by other types of cells than Tc and Th

19
Q

Tone down T cell response to self cells or following an infection

A

Regulatory or suppressor T cells

20
Q

T cells
Develop?
Mature ?

A

Bone marrow

Thymus

21
Q

Low levels of T cells , subject to infection

A

Aids

22
Q

B lymphocytes
Development ?
Mature?

A

Both In bone marrow

23
Q

Expressed by B cells , provide specific targeted responses to a given antigen

A

Antibodies / immunoglobulins

24
Q

Structure of antibodies ?

A

Light chain
Heavy chain
Disulfide bridges

25
Q

Occurs as a result of an immune response : vaccination or pathogen/antigen. Memory T cells are produced

A

Active immunity

26
Q

Acquired through transfer of antibodies such as during pregnancy or injections of gamma globulin . Immunity is lost once out of circulation

A

Passive immunity

27
Q

4 things innate immunity includes

A

Anatomic feature : integument
Physiological : fever , pH , enzymes
Phagocytic cells: monocytes neutrophils macrophages
Inflammation

28
Q

Cells capable of recognizing self vs non self

A

Acquired or specific immunity

29
Q

3 cells involved in adaptive immunity

A

Lymphocytes : b and T cells
Plasma cells
Antigen presenting cells : macrophages B cells

30
Q

Where is the antigen binding region found on the immune globulin

A

N terminus