Integrative Tissue Metabolism. Flashcards
What is Adipose tissue made of?
Adipocytes (fat cells).
What is metabolic activity of Adipose Tissue?
Very metabolically active. 2nd to only Skeletal Muscle.
How does Adipose Tissue respond?
Through hormones.
What percentage mass of a young adult is Adipose tissue?
15%.
How is the energy of TAG released?
When hormones signal need for metabolic energy, the TAG’s are mobilised and transported to tissues.
What happens to the actual stuff in TAG for energy production?
Fatty acids are oxidised via BETA-oxidation to produce energy and Glycerol can be used for energy production or GNG.
At rest, what percentage of the energy can be attributed to skeletal muscle?
20%.
During active muscular work, what percentage of the energy can be attributed to skeletal muscle?
90%.
What can Skeletal Muscle use as energy?
EVERYTHING.
What is the energy source for skeletal muscle at rest?
Fatty acids from adipose. 80%.
What is the energy source for skeletal muscle at short bursts of energy?
Creatine Phosphate.
What is short burst?
First few minutes.
What enzymes the synthesis of creatine phosphate?
Creatine phosphokinase.
What is the energy source for skeletal muscle at moderately active?
Glucose from it’s own glycogen stores and Liver’s stores and fatty acids and ketones.
What is the energy source for skeletal muscle at extremely active?
Muscle glycogen –> Lactate. Cori cycle also occurs in liver where the lactate will be converted to glucose.
What is the energy source for skeletal muscle at starvation?
Ketosis or protein breakdown.
Rate of metabolism for cardiac muscle?
High metabolism, continually active.
What lipid and glycogen stores does cardiac muscle have?
Not much.
What is the primary fuel for heart muscle?
Fatty acids.
What type of respiration does the heart muscle undergo?
Aerobic.
What other fuels can the cardiac muscle use?
Glucose and ketones.
What fuel reserves does brain muscle have?
None.
What is the primary fuel source?
Glucose from diet or liver.
What does brain use in fasting conditions?
Ketones. They can cross blood barrier.
