Integrative MSK Flashcards
MA woman, progressive weakness
problems rising from chair
dec strength in proximal LE bilateerally
CK is elevated
dx is ___/____
mechanism is ___ inflammation of muscle
polymyositis/dermatomyositis
immune mediated
elderly woman, progressive bilateral knee pain
no redness/swelling
hypertrophy over DIP/PIP, crepitus
dx is ___
osteoporosis
YAW, pain/swelling in wrists/knuckles/fingers
worse in AM
swelling in multiple joints
lump on extensor surfaces
no rash/ulcers
dx is ____
early antibody is ____
RA
anti-CCP
MA woman, dysphagia of solids/liquids
skin on hands/fingers is tighter, sensitive to cold weather
nodules on forearms
dx is ____
antibody is ____
CREST
anti-centromere
YA woman, diffuse joint pain, fatigue/myalgia, fever
rash on face, pleurisy
dx is ____
antibodies include __/___
SLE
ANA/ani DS DNA
MA woman w weakness, rash on eyelids, difficulty swallowing
dec strength in proximal muscles, purple rash on eyelids/knuckles
CK is inc
dx is ___
antibodies include /__/
dermatomyositis
anti-Jo1/anti SRP/anti Mi2
ma woman w dry, itchy eyes, dry mouth, ulcerated corneas
dx is ___
ab present ____
sjogrens
anti-Ro./La
elderly man, fatigue and low grade fevers
hip/shoulder pain, tenderness over trapezius/deltoid/trochanter
strength is ___
___is inc
dx is _____
normal
ESR
polymyalgia rheumatica
Arthralgia, photosensitivity, serositis, rash, cytopenias
dx is ____
sensitive Ab ___
specific ab for lupus nephritis __/___
SLE
ANA
anti-DS DNA, anti-Smith ab
AM stiffness, symmetric, small joints of hand/feet, sub q nodules, joint erosions
dx is ___
RA
dry eyes/mouth
dx is ___
ab nclude __/___
may be positive for __/___
sjogrens
anti SSA (Ro) or anti SSb (la)
ANA, RF
YA male, low back pain, worse in AM
bilateral, forward bend, tender in SI joints, cannot touch toes
erosions in SI joint
dx is ___
AS
painful, swollen, knee
high fever, effusion, red
inc WBC in arthrocentesis, no crystals
dx is _____
causative org is probably __
do __ to dx
septic arthritis
staph aureus
arthrocentesis
YA woman, wrist/knee swelling, migratory pains
effusion in knee, papules on lower extremities
scant mucoid discharge from pelvis
dx is ____
causative organism is ___
gonococcal arhritis
n gonorhea
MA man, swelling in ankle
red, warm, swollen, negatively birefringent crystals
dx is ___
gout
Elderly male, knee pain/sweling
xray shows chondrocalcinosis
dx is ____
may be associated w __/__
crystals are __
___ birefringent, __ in parallel
pseudogout
Hemochromatosis, hyperPTH
rhomboid
+, blue
tx acute gout w __ or __
chronic w ___ such as __
NSAIDs, colchicine
XO inhibitor, allopurinol
conjunctivitis, urethritis, uveitis
dx is ___
causative orgs S Y C C S
reactive arthritis
shigella yersinia campyl chlamydia salmonella
sausage shaped digits, arthritis, scaly rash on limbs
dx is __
psoriatic arthritis