Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Adv Biochem > Integration of Metabolism > Flashcards

Integration of Metabolism Flashcards

1
Q

Overview of Carbohydrate Metabolism in Liver

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Overview of Amino Acid Metabolism in Liver

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Overview of Lipid Metabolism in Liver

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Adipose tissue stores and supplies _______.

A

Fatty acids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

About ____% of adipose tissue is fat.

A

65

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Major metabolic pathways in Adipose Tissue

A
  • Glycolytic metabolism
  • TCA cycle
  • Oxidative Phosphorylation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Some adipose tissue contains ________.

A

Brown fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How do muscles use ATP for mechanical work?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Conversion of phosphocreatine and creatine

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The Cori cycle

A

Glucose –> Lactate –> Glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Brain uses ____ for impulse transmission.

A

ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How does the brain use and produce ATP?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does the blood carry?

A

O2, Metabolites, Hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Composition of the blood

A
  • Inorganic components (10%)
  • Organic metabolites and waste (20%)
  • Plasma proteins (70%)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Normal blood glucose level & dangerous level

A
  • 60-90 mg/dL
  • 40 mg/dL
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Hormonal regulation of Fuel Metabolism: Insulin is synthesized as _____ precursor.

A

Inactive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Insulin counters high blood glucose

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Increase in glucose uptake in muscle and adipose targets ________.

A

Increase in Glucose Transporter (GLUT4)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Increase in glucose uptake in the liver targets ________.

A

Increase in glucokinase (increased expression)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Increase in glycogen synthesis in the liver and muscle targets _______.

A

Increase in glycogen synthase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Decrease in glycogen breakdown in the liver and muscle targets ________.

A

Decrease in glycogen phosphorylase

22
Q

Increase in glycolysis/acetyl-CoA production in liver and muscle targets ________.

A
  • Increase in PFK-1 by increase in PFK-2
  • Increase in pyruvate dehydrogenase
23
Q

Increase in fatty acid synthesis in the liver targets _______.

A

Increase in acetyl-CoA carboxylase

24
Q

Increase in triacylglycerol synthesis in adipose tissue targets _________.

A

Increase in lipoprotein lipase

25
Regulation of glycogen synthase or glycogen biosynthesis
26
Regulation of glycogen phosphorylase by covalent modification
27
Regulation of fatty acid synthesis
28
Hormonal regulation of triacylglycerol synthesis
29
Glucagon counters low blood glucose
30
Increase in glycogen breakdown in the liver converts glycogen to glucose and targets \_\_\_\_\_\_\_\_\_.
Increase in glycogen phosphorylase
31
Decrease in glycogen synthesis in the liver means less glucose is stored as glycogen and targets \_\_\_\_\_\_\_\_\_.
Decrease in glycogen synthase
32
Decrease in glycolysis in the liver means less glucose is used as fuel in the liver and targets and targets \_\_\_\_\_\_\_.
Decrease in PFK-1
33
Increase in gluconeogenesis in the liver means amino acids, glycerol, and oxaloacetate are converted to glucose and targets \_\_\_\_\_\_\_\_\_.
- Increase in FBPase-2 - Decrease in Pyruvate kinase - Increase in PEP carboxykinase
34
Increase in fatty acid mobilization in adipose tissue means less glucose is used as fuel by liver and muscle and targets \_\_\_\_\_\_\_.
- Increase in hormone-sensitive lipase - Increase in PKA
35
Increase in ketogenesis provides an alternative to glucose as energy source for brain and targets \_\_\_\_\_\_.
Decrease in acetyl-CoA carboxylase
36
Regulation of PFK-2 and F26BP
37
Mobilization of stored triacylglycerol
38
Increase in heart rate, blood pressure, and dilation of respiratory passages leads to \_\_\_\_\_\_\_\_.
Increase delivery of O2 to tissues (muscle)
39
Increase in glycogen breakdown, decrease in glycogen synthesis in muscle and liver, and increase in gluconeogenesis in liver leads to \_\_\_\_\_\_\_\_\_\_.
Increase producation of glucose for fuel
40
Increase in glycolysis in the muscle leads to \_\_\_\_\_\_\_.
Increases ATP production in muscle
41
Increase in fatty acid mobilization in adipose tissue leads to \_\_\_\_\_\_\_.
Increase availability of fatty acids as fuel
42
Increase in glucagon secretion and decrease in insulin secretion leads to \_\_\_\_\_\_\_\_\_.
Reinforcement of metabolic effects of epinephrine
43
During fasting and starvation, metabolism shifts to provide fuel to the brain. A normal weight man (70 kg) could survive _____ and an obese man (140 kg) could survive \_\_\_\_\_\_.
- 3 months - 14 months
44
Fuel metabolism in liver during prolonged fasting or uncontrolled diabetes mellitus
45
Ketone body formation
46
Carbohydrate catabolism
47
Carbohydrate anabolism
48
Amino acid and nucleotide metabolism
49
Fat catabolism
50
Fat anabolism

Adv Biochem (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions