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Biochemistry > Integration Of Metabolism > Flashcards

Integration Of Metabolism Flashcards

0
Q

End product under anaerobic condition in glycolysis

A. Lactate
B. Pyruvate

A

A. Lactate

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1
Q

Glycolysis is controlled through the activity of

A

Phosphofructokinase

Activated by: AMP, ADP, fructose2,6 bisohosphate
Inhibited by: ATP and citrate

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2
Q

End product of glycolysis during aerobic state

A. Lactate
B. Pyruvate

A

B. Pyruvate

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3
Q

Substrate in gluconeogenesis

A. Glucose
B. Pyruvate, lactate, glycerol, glucogenic acid
C. Glucose-6-phosphate
D. Glycogen

A

B.

Rate limiting enzyme in gluconeogenesis: fructose-1,6-bisphosphate
End product: glucose

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4
Q

Substrate in glycogenesis

A. Glucose
B. Pyruvate, lactate, glycerol, glucogenic acid
C. Glucose-6-phosphate
D. Glycogen

A

C.

Glycogenesis maintain energy needed for the muscles or to maintain serum glucose during fasting periods

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5
Q

Rate limiting enzyme in glycogenesis

A

Glycogen synthase

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6
Q

Rate limiting enzyme in glycolysis

A

PFK1

Substrate: glucose

Major pathway for glucose metabolism

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7
Q

Substrate in glycogenolysis

A. Glucose
B. Pyruvate, lactate, glycerol, glucogenic acid
C. Glucose-6-phosphate
D. Glycogen

A

D. Glycogen

Rate limiting enzyme: glycogen phosphorylase
End product: glucose-6-phosphate

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8
Q

Rate limiting enzyme in glycogenesis

A. Glycogen phosphorylase
B. Glycogen synthase
C. PFK1
D. Fructose-1,6-bisphosphate

A

B. Glycogen synthase

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9
Q

Rate limiting enzyme in glycogenolysis

A. Glycogen phosphorylase
B. Glycogen synthase
C. PFK1
D. Fructose-1,6-bisphosphate

A

A. Glycogen phosphorylase

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10
Q

Rate limiting enzyme in gluconeogenesis

A. Glycogen phosphorylase
B. Glycogen synthase
C. PFK1
D. Fructose-1,6-bisphosphate

A

D.

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11
Q

Fatty acid synthesis incorporates carbon from ACETYL COA into the growing FA chain using ATP and NADPH which occurs in

A. Mitochondria
B. Cytosol

A

B. Cytosol

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12
Q

Beta oxidation of fatty acid is the major energy producing pathway which occurs in

A. Mitochondria
B. Cytosol

A

A. Mitochondrial matrix UREA cycle

Beta oxidation of FA are series of reactions that produces urea from ammonia which occurs in the LIVER

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13
Q

Citric acid cycle a major energy providing pathway which occurs in the

A. Mitochondria
B. Cytosol

A

A. Mitochondrial matrix(same with beta oxidation of FA)

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14
Q

Electron transport chain pathway happens in

A. Inner mitochondria
B. Outer mitochondria

A

A. Inner mitochondria

NADPH plus H+ and FADH2 are used to generate ATP

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15
Q

Rate limiting enzyme in UREA CYCLE

A. Carnitine acyl-transferase-I
B. Acetyl-CoA carboxylase
C. Carbamoyl phosphate synthetase-I
D. Isocitrate dehydrogenase

A

C. Carbamoyl phosphate synthetase I

Substrate: NH4 and aspartate
Product: UREA

16
Q

End product in ETC

A. Urea
B. Free palmitate
C. ATP, H2O
D. ATP, H2o, NADH, FADH

A

C. ATP, H2o

17
Q

End product in CAC

A. Urea
B. Free palmitate
C. ATP, H2O
D. ATP, H2o, NADH, FADH

A

D.

18
Q

End product in beta oxidation of FA

A. Urea
B. Free palmitate
C. ATP, H2O
D. Acetyl-CoA

A

D. Acetyl coa

19
Q

End product in fatty acid synthesis

A. Urea
B. Free palmitate
C. ATP, H2O
D. ATP, H2o, NADH, FADH

A

B. Free palmitate

20
Q

Rate limiting enzyme in beta oxidation of FA

A

Carnitine palmitoyl/acyl transferase I

21
Q

Pentose phosphate pathway happens in the _______ state

A. Well fed
B. Starvation
C. Fasting

A

A. Well fed

22
Q

Alternative pathway for the metabolism of glucose

A. CAC
B. ETC
C. Ppp

A

C. PPP

23
Q

Substrate and rate limiting enzyme in PPP

A. Glucose 5-phosphate; G5PD
B. Glucose 6 phosphate; G6PD
C. Ribose5-phosphate and NADPH

A

B.

24
Q

End product in PPP

A. Glucose 5-phosphate; G5PD
B. Glucose 6 phosphate; G6PD
C. Ribose5-phosphate and NADPH

A

C.

25
Q

What are the 4 metabolic fuels

A

Glucose, fatty acids, ketone bodies, amino acids

26
Q

True or false: high carbohydrate diet spares fatty acid oxidation

A

True

27
Q

True or false: oxidation of fatty acids and ketone bodies spares glucose oxidation

A

True

Biochemistry (6 decks)

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