Integrating Cells and Tissues Flashcards
1
Q
Name two ways a cell can be adhered to the basement membrane?
A
Hemidesmosomes - Basement membrane to cell via a plaque, intermediate filaments and integrins.
Focal adhesions - Basement membrane to the actin filaments in the cytoskeleton via integrins.
2
Q
Name a way cell can be adhered to ECM?
A
Via integrins
3
Q
Name 4 roles of integrins
A
Attach from actin in cytoskeleton to ECM
Signal transduction from ECM to cell
Role in immunity and cell migration
4
Q
Name 4 cell-cell junctions/adhesions
A
Desmosomes
Tight junctions
Gap junctions
Adherens
5
Q
What is the cytoskeleton made up of?
A
Actin, microtubules, intermediate filaments
