Insulins Flashcards

1
Q

Name 2 long-acting insulin analogs.

A
  1. Glargine
  2. Detemir
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2
Q

What is the onset for the long-acting insulin analogs?

A

1-1.5 hrs

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3
Q

What is the peak of the short-acting human insulins?

A

2 hrs

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4
Q

What is the function of basal insulin (glargine, detemir, NPH)?

A

to suppress hepatic glucose output and lower glucose levels even when the pt is fasting

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5
Q

Insulin type?

  • Humalog
  • novolog
  • glulisine
A

rapid-acting insulin analogs

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6
Q

What is the duration of the rapid-acting insulin analogs?

A

3-5 hours

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7
Q

The standard of care for glycemic management in DMI is _________.

A

basal bolus therapy (intensive, multiple dose insulin)

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8
Q

How are the long-acting insulin analogs administered?

A

sub-q only

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9
Q

What are some negatives to using pre-mixed insulins?

A

you have to keep a very set schedule

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10
Q

What is the peak of the rapid-acting insulin analogs?

A

1-1.5 hours

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11
Q

Name 3 intermediate-acting insulin analogs.

A
  1. NPH
  2. Humulin
  3. Novolin
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12
Q

What is the onset for the intermediate-acting insulin analogs?

A

1-3 hours

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13
Q

What is the duration for the intermediate-acting insulin analogs?

A

12-16 hrs

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14
Q

What is the peak for the intermediate-acting insulin analogs?

A

6-8 hours

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15
Q

What is the onset of the short-acting human insulins?

A

30-60 mins

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16
Q

When is insulin therapy used?

A
  • DMI
  • hospitalizations
  • pregnancy
17
Q

What is the duration of the short-acting human insulins?

A

6-8 hrs

18
Q

What are some positives to using pre-mixed insulins?

A
  • minimal injections (only 2/day)
  • good for set schedules
19
Q

These insulins are used to “correct” a high blood glucose level.

A

correctional insulin (Humalog, Novolog, inhaled)

20
Q

What is the peak for the long-acting insulin analogs?

A

none

21
Q

Insulin type?

  • NPH
  • Humulin
  • Novolin
A

intermediate-acting insulin analogs

22
Q

What is the function of prandial insulin (rapid-acting or regular insulin)?

A

to metabolize nutrients in a meal or snack and cover the postprandial rise in glucose

23
Q

Insulin type?

  • Humulin R
  • Novolin R
A

short-acting human insulins

24
Q

How are the short-acting human insulins administerd?

A
  • sub-Q or IV
  • 30 mins before eating
25
Q

How are the intermediate-acting insulin analogs administered?

A
  • sub-q only
  • 2x/day
26
Q

These insulins are used to metabolize nutrients in a meal or snack and cover the postprandial rise in glucose.

A

prandial insulin (rapid-acting or regular insulin)

27
Q

What is the onset of the rapid-acting insulin analogs?

A

5-15 mins

28
Q

Name 2 short-acting human insulins.

A
  1. Humulin R
  2. Novolin R
29
Q

How are the rapid-acting insulin analogs administered?

A

sub-q or pump before a meal inhaled form

30
Q

These insulins are used to suppress hepatic glucose output and lower glucose levels even when the pt is fasting.

A

basal insulins (glargine, detemir, NPH)

31
Q

What is the function of correctional insulin (Humalog, Novolog, inhaled)?

A

to “correct” a high blood glucose level

32
Q

What is the duration for the long-acting insulin analogs?

A

12-20 (detemir) or 24 hrs (glargine)

33
Q

What is unique about the intermediate-acting insulin analogs?

A

they’re cloudy

34
Q

Insulin type?

  • Glargine
  • Detemir
A

long-acting insulin analogs

35
Q

Name 3 rapid-acting insulin analogs.

A
  1. Humalog
  2. novolog
  3. glulisine