Insulins Flashcards

1
Q

Name 2 long-acting insulin analogs.

A
  1. Glargine
  2. Detemir
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2
Q

What is the onset for the long-acting insulin analogs?

A

1-1.5 hrs

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3
Q

What is the peak of the short-acting human insulins?

A

2 hrs

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4
Q

What is the function of basal insulin (glargine, detemir, NPH)?

A

to suppress hepatic glucose output and lower glucose levels even when the pt is fasting

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5
Q

Insulin type?

  • Humalog
  • novolog
  • glulisine
A

rapid-acting insulin analogs

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6
Q

What is the duration of the rapid-acting insulin analogs?

A

3-5 hours

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7
Q

The standard of care for glycemic management in DMI is _________.

A

basal bolus therapy (intensive, multiple dose insulin)

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8
Q

How are the long-acting insulin analogs administered?

A

sub-q only

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9
Q

What are some negatives to using pre-mixed insulins?

A

you have to keep a very set schedule

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10
Q

What is the peak of the rapid-acting insulin analogs?

A

1-1.5 hours

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11
Q

Name 3 intermediate-acting insulin analogs.

A
  1. NPH
  2. Humulin
  3. Novolin
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12
Q

What is the onset for the intermediate-acting insulin analogs?

A

1-3 hours

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13
Q

What is the duration for the intermediate-acting insulin analogs?

A

12-16 hrs

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14
Q

What is the peak for the intermediate-acting insulin analogs?

A

6-8 hours

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15
Q

What is the onset of the short-acting human insulins?

A

30-60 mins

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16
Q

When is insulin therapy used?

A
  • DMI
  • hospitalizations
  • pregnancy
17
Q

What is the duration of the short-acting human insulins?

18
Q

What are some positives to using pre-mixed insulins?

A
  • minimal injections (only 2/day)
  • good for set schedules
19
Q

These insulins are used to “correct” a high blood glucose level.

A

correctional insulin (Humalog, Novolog, inhaled)

20
Q

What is the peak for the long-acting insulin analogs?

21
Q

Insulin type?

  • NPH
  • Humulin
  • Novolin
A

intermediate-acting insulin analogs

22
Q

What is the function of prandial insulin (rapid-acting or regular insulin)?

A

to metabolize nutrients in a meal or snack and cover the postprandial rise in glucose

23
Q

Insulin type?

  • Humulin R
  • Novolin R
A

short-acting human insulins

24
Q

How are the short-acting human insulins administerd?

A
  • sub-Q or IV
  • 30 mins before eating
25
How are the intermediate-acting insulin analogs administered?
* sub-q only * 2x/day
26
These insulins are used to metabolize nutrients in a meal or snack and cover the postprandial rise in glucose.
prandial insulin (rapid-acting or regular insulin)
27
What is the onset of the rapid-acting insulin analogs?
5-15 mins
28
Name 2 short-acting human insulins.
1. Humulin R 2. Novolin R
29
How are the rapid-acting insulin analogs administered?
sub-q or pump before a meal inhaled form
30
These insulins are used to suppress hepatic glucose output and lower glucose levels even when the pt is fasting.
basal insulins (glargine, detemir, NPH)
31
What is the function of correctional insulin (Humalog, Novolog, inhaled)?
to "correct" a high blood glucose level
32
What is the duration for the long-acting insulin analogs?
12-20 (detemir) or 24 hrs (glargine)
33
What is unique about the intermediate-acting insulin analogs?
they're cloudy
34
Insulin type? * Glargine * Detemir
long-acting insulin analogs
35
Name 3 rapid-acting insulin analogs.
1. Humalog 2. novolog 3. glulisine