Gluconeogenesis Flashcards
_______ is the process by which glucose is synthesized from non-carbohydrate precursors.
Gluconeogenesis
Where does gluconeogenesis take place?
in the cytosol
Where is pyruvate carboxylase located?
in the mitochondria
What tissues can perform gluconeogenesis?
the liver and kidney
When does gluconeogenesis occur?
during fasting, intense exercise, low carb/high protein diet, stressful conditions, insulin resistance/DMII
Which tissues rely on glucose as their sole or major source of energy?
brain RBCs renal medulla sperm embryonic tissue
The main sources of carbon skeletons for gluconeogenesis are _____, _____, and _____.
lactate
aa’s
glycerol
Are fatty acids converted to glucose?
no- but they are used for energy for gluconeogenesis
What is the Cori cycle?
glucose –> lactic avid –> pyruvate –> gluconeogenesis
What does gluconeogenesis start with?
pyruvate
____ deficiency leads to the build up of pyruvate, which leads to lactic acid and leads to lactic acidosis.
Biotin
