Insulins Flashcards
glipizide (Glucotrol)glyburide (Glynase)glimepiride (Amaryl)
2nd generation sulfonylureas
glipizide (Glucotrol)glyburide (Glynase)glimepiride (Amaryl)ACTION
Works to increase output of insulin by beta cells in pancreas
glipizide (Glucotrol)glyburide (Glynase)glimepiride (Amaryl)Nx Implications
Best taken 30 min prior to mealMain potential side effects: hypoglycemia with delayed or skipped meals or alcoholUse cautiously in elderly
metformin Glucophage
Biguanide
metformin GlucophageACTION
Decrease liver output of sugarIncrease peripheral insulin sensitivity
metformin GlucophageNx Implication
Kidney surveillance testing required (monitor serum creatinine)Contraindicated if pt has CHG, alcohol abuse, metabolic acidosis, liver or kidney disease, or > 80 years oldMain potential side effects: GI distress/diarrhea, lactic acidosisTake with foodDiscontinue after OR, dye studies for 48 hours or until kidney function normal
InsulinNx Implications
Monitor blood sugar levelWhen mixing, draw rapid acting first (clear before cloudy)
lispro Humalogaspart NovalogCLASS
Very rapid acting
lispro Humalogaspart NovalogACTION
Onset: 10 minPeak: 1hrDuration: 3-4hrs
lispro Humalogaspart NovalogNx Implication
Clear solutionGive 15 min prior to meal
Regular RCLASS
Short (rapid) acting
Regular RACTION
Onset: 30 minPeak: 3-5hrsDuration: 6-10hrs
Regular RNx Implication
Clear solutionGive 30 min prior to meal
NPHLenteCLASS
Intermediate acting
NPHLenteACTION
Onset: 1hrPeak: 6-12hrsDuration: 20-24hrs