Antibiotics Flashcards
Penicillin mechanism of action
Cell wall synthesis inhibitors
Penicillin Adverse Effects
N/V Diarrhea Superinfections Anaphylaxis Decreased RBC, WBC, or platelet count
Penicillin Nx Implications
Take on empty stomach
Monitor for hyperkalemia and hypernatremia
Monitor cardiac status
Cephalosporin prototype drug
cefotaxime Claforan
Cephalosporincefotaxime (Claforan) mechanism of action
Broad spectrum cell wall synthesis inhibitor
Cephalosporincefotaxime (Claforan) adverse effects
N/V Diarrhea Hypersensitivity Anaphylaxis Pain at injection site
Cepholosporincefotaxime (Claforan) Nx implication
Take with food
Assess for presence or history of bleeding disorders (may reduce prothrombin levels)
Avoid alcohol, some cause Antabuse
Tetracycline prototype drug
tetracycline HCL (Achromycin)
tetracycline mechanism of action
Broad spectrum Protein synthesis inhibitors
tetracycline primary use
chlamydiae
rickettsiae
mycoplasma
tetracycline adverse effects
N/V Diarrhea Superinfections Epigastric burning Discoloration of teeth* Photosensitivity* Can effect liver & kidneys*
tetracycline Nx Implication
Do not take with calcium or iron
Do not give to children under 8
Contraindicated if pregnant
Aminoglycoside prototype drug
gentamicin (Garamycin)
Aminoglycosidegentamicin mechanism of action
Narrow spectrum bacteriocidal Inhibit protein synthesis
Aminoglycosidegentamicin primary use
Serious urinary, respiratory, nervous, or GI infections