Antibiotics Flashcards

1
Q

Penicillin mechanism of action

A

Cell wall synthesis inhibitors

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2
Q

Penicillin Adverse Effects

A
N/V
Diarrhea
Superinfections
Anaphylaxis
Decreased RBC, WBC, or platelet count
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3
Q

Penicillin Nx Implications

A

Take on empty stomach
Monitor for hyperkalemia and hypernatremia
Monitor cardiac status

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4
Q

Cephalosporin prototype drug

A

cefotaxime Claforan

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5
Q

Cephalosporincefotaxime (Claforan) mechanism of action

A

Broad spectrum cell wall synthesis inhibitor

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6
Q

Cephalosporincefotaxime (Claforan) adverse effects

A
N/V
Diarrhea
Hypersensitivity
Anaphylaxis
Pain at injection site
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7
Q

Cepholosporincefotaxime (Claforan) Nx implication

A

Take with food
Assess for presence or history of bleeding disorders (may reduce prothrombin levels)
Avoid alcohol, some cause Antabuse

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8
Q

Tetracycline prototype drug

A

tetracycline HCL (Achromycin)

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9
Q

tetracycline mechanism of action

A

Broad spectrum Protein synthesis inhibitors

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10
Q

tetracycline primary use

A

chlamydiae
rickettsiae
mycoplasma

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11
Q

tetracycline adverse effects

A
N/V
Diarrhea
Superinfections
Epigastric burning
Discoloration of teeth*
Photosensitivity*
Can effect liver & kidneys*
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12
Q

tetracycline Nx Implication

A

Do not take with calcium or iron
Do not give to children under 8
Contraindicated if pregnant

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13
Q

Aminoglycoside prototype drug

A

gentamicin (Garamycin)

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14
Q

Aminoglycosidegentamicin mechanism of action

A

Narrow spectrum bacteriocidal Inhibit protein synthesis

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15
Q

Aminoglycosidegentamicin primary use

A

Serious urinary, respiratory, nervous, or GI infections

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16
Q

Aminoglycosidegentamicin adverse effects

A

Ototoxicity

Nephrotoxicity

17
Q

Aminoglycosidegentamicin Nx Implication

A

Monitor for ototoxicity and nephrotoxicity

Increase fluid intake

18
Q

Fluoroquinolones prototype drug

A

ciprofloxacin (Cipro)

19
Q

Fluoroquinolonesciprofloxacin mechanism of action

A

Inhibit bacterial DNA gyrase

20
Q

Fluoroquinolonesciprofloxacin adverse effects

A
N/V
Diarrhea
Photosensitivity*
Headache
Dizziness
21
Q

Fluoroquinolonesciprofloxacin Nx Implications

A

Do not take with multivitamins or minerals*
Most serious adverse effects are dysrhythmias and liver failure
Do not use in children and pregnant or lactating women

22
Q

Sulfonamides prototype drug

A

trimethoprim-sulfamethoxazole (Bactrim, Septra)

23
Q

Sulfonamidestrimethoprim (Bactrim) mechanism of action

A

Broad spectrum that inhibits bacterial metabolism of folic acid

24
Q

Sulfonamidestrimethoprim (Bactrim) primary use

A

UTI*

25
Q

Sulfonamidestrimethoprim (Bactrim) adverse effects

A

N/V
Skin rashes
Agranulocytosis
Thrombocytopenia

26
Q

Sulfonamidestrimethoprim (Bactrim) Nx Implication

A

Assess for anemia or other hematological disorders
Assess renal function*
Teach how to decrease effects of photosensitivity
Take with lots of water*

27
Q

Vancomycin (Vancocin) effective for

A

MRSA infections

28
Q

Vancocin adverse effects

A

Ototoxicity
Nephrotoxicity
Red man syndrome
Considered a big gun

29
Q

Erythromycin mechanism of action

A

Protein synthesis inhibitor

30
Q

Erythromycin Adverse effects

A

N/V
Hearing loss
Vertigo
Dizziness

31
Q

Erythromycin

Nx Implication

A

Administer on empty stomach
Full glass of water
Do not give with, before, or after fruit juices