Analgesics Class 4

Question 1

Opioid prototype drug

Answer 1

morphine

Question 2

morphine
Opioid Analgesic
Action

Answer 2

Activates mu and kappa receptors

Question 3

morphine
Opioid Analgesic
Primary Use

Answer 3

Analgesia

Anesthesia

Question 4

morphine
Opioid Analgesic
Adverse effects

Answer 4

Respiratory depression
Sedation
Constipation
N/V

Question 5

Opioid Antagonist

prototype drug

Answer 5

Narcan

Question 6

Opioid Antagonist

Action

Answer 6

Blocks mu and kappa receptors

Question 7

Opioid Antagonist

Primary Use

Answer 7

Reverse respiratory depression

Question 8

Treatment for Opioid Dependence

Answer 8

Methadone maintenance

Question 9

Nonopioid Analgesic

Prototype drug

Answer 9

Acetaminophen Tylenol

Question 10

Nonopioid Analgesic
Acetaminophen
Action

Answer 10

Treats mild pain by mildly inhibiting prostaglandins

Reduces fever by vasodilation

Question 11

Nonopioid Analgesic
Acetaminophen
Primary Use

Answer 11

Antipyretic

Analgesic

Question 12

Nonopioid Analgesic
Acetaminophen
Adverse Effects

Answer 12

Overdoses are lethal

Question 13

NSAID
ibuprofen
Action

Answer 13

Inhibits COX receptors and prevents formation of prostaglandins

Question 14

NSAID
ibuprofen
Primary Use

Answer 14

Analgesic

Anti-inflammatory

Question 15

NSAID
ibuprofen
Adverse effects

Answer 15

GI upset

Acute renal failure

Question 16

Salicylates
Aspirin
Primary use

Answer 16

Anticoagulant
Antipyretic
Anti-inflammatory
Analgesic

Question 17

Salicylates
Aspirin
Adverse effects

Answer 17

Bleeding
GI distress
Increase action of oral hypoglycemics

Question 18

Selective COX-2 Inhibitors
celecoxib Celebrex
Action

Answer 18

Inhibits COX-2 to prevent formation of prostaglandins

Question 19

Selective COX-2 Inhibitors
celecoxib Celebrex
Primary Use

Answer 19

Analgesic
Antipyretic
Anti-inflammatory

Question 20

Selective COX-2 Inhibitors
celecoxib Celebrex
Adverse effects

Answer 20

Mild and related to GI

Question 21

Antimigraine
sumatriptan (Imitrex)
Action

Answer 21

Serotonin agonists

Constrict intracranial vessels

Question 22

Antimigraine
sumatriptan (Imitrex)
Primary use

Answer 22

Abort migraines

Question 23

Antimigraine
sumatriptan (Imitrex)
Adverse effects

Answer 23

GI upset

Increase BP

Question 24

Antimigraine
ergotamine tartrate (Ergostat)
Action

Answer 24

Promote vasoconstriction

Question 25

Antimigraine
ergotamine tartrate (Ergostat)
Primary use

Answer 25

Terminate ongoing migraines

Question 26

Antimigraine
ergotamine tartrate (Ergostat)
Adverse effects

Answer 26

S/S of vasoconstriction or decrease in blood flow

ie. numbness, tingling, angina-like pain, tachycardia

Question 27

What 4 drugs treat prophylaxis of migraines?

Answer 27

Beta blockers
Calcium channel blockers
Antidepressants
Antiseizures

Question 28

Stimulation of Histamine 1 receptors

Answer 28

Itching
Pain
Edema
Vasodilation
Bronchoconstriction

Question 29

Stimulation of Histamine 2 receptors

Answer 29

Secretion of hydrochloric acid in the stomach

Question 30

Inhibition of COX-1

Answer 30

Bleeding
Gastric upset
Reduced renal function

Question 31

Inhibition of COX-2

Answer 31

Suppresses inflammation

Question 32

Systemic glucocorticoids
prednisone Meticorten
Action

Answer 32

Suppresses histamine and prostaglandins

Question 33

Systemic glucocorticoids
prednisone Meticorten
Primary use

Answer 33

Treat inflammation

Question 34

Systemic glucocorticoids
prednisone Meticorten
Adverse effects

Answer 34

Long term: Cushing’s syndrome, adrenal gland atrophy, cataracts, corticosteroids, peptic ulcers
Short term: insomnia, increased energy, GI upset, increased appetite

Question 35

Salicylates
Aspirin
Contraindication

Answer 35

Pediatrics

Reye’s Syndrome: confusion, lethargy, altered LOC, N/V