Insomnia Drugs

Question 1

Barbituates for sleep

Answer 1

Not used

Question 2

Zolpidem

Answer 2

Z drug

Intermediate half life. Use to fall asleep and stay asleep

Question 3

Zaleplon

Answer 3

Z drug

Short. Use for if you wake up in the middle of the night and need to get back to sleep

Question 4

Eszoplicone

Answer 4

Z drug

Long. More for long term

Question 5

Z drug mechanism

Answer 5

bind gamma of a1 GABA receptors = faciliate opening

Question 6

Z drug side effects

Answer 6

drowsiness, dizziness, headache

Question 7

Triazolam

Answer 7

Benzo. Short

Question 8

Temazepam

Answer 8

Benzo Intermediate

Question 9

Flurazepam

Answer 9

Benzo. Long

Question 10

Triazolam Side Effects

Answer 10

Dose reduction in elderly.

Question 11

Flurazepam Side Effects

Answer 11

Can accumulate from impaired hepatic clearance = daytime sedation

Question 12

Trazadone for Sleep

Answer 12

Inhibition 5HT reuptake, agonist, & antagonist

Good for patients w/abuse history

Question 13

Trazadone Side Effects

Answer 13

Oversedation & orthostasis

Priapism

Question 14

TCAD for Sleep

Answer 14

For patients who shouldn’t receive benzos

Question 15

TCAD Side Effects

Answer 15

Antimuscarinic & antiadrengeric effects

Question 16

Ramelton

Answer 16

MT1 & 2 agonist

Use to help fall asleep

Question 17

Ramelton Side Effects

Answer 17

Dizziness, somnolence, fatigue, nausea

Question 18

Antihistamines

Answer 18

H1 and muscarinic antagonist. Short term. NOT RECOMMENDED

Question 19

Antihistamine Side Effects

Answer 19

Antimuscarinic (esp. elderly)

Question 20

Chloral Hydrate

Answer 20

Transient insomnia. From 1800s.