Anxiolytics Flashcards
1
Q
Diazepam
A
Benzodiazepine
2
Q
Alprazolam
A
Potent Benzo
3
Q
Lorazepam
A
Benzo
4
Q
Oxazepam
A
Benzo
5
Q
Midazolam
A
Benzo
6
Q
Benzo Mechanism
A
Act by intensifying GABA channel Cl current only if GABA is present
7
Q
Buspirone
A
5HT1A partial agonist, some affinity for D2. No sedation or CNS affects.
8
Q
Pentobarbital
A
Barbiturate
9
Q
Phenobarbital
A
Barbiturate
10
Q
Barbiturate Mechanism
A
Increases duration of Cl channel opening even in absence of GABA if high enough dosage
11
Q
Clonazepam
A
Potent Benzo
12
Q
Flumazenil
A
Benzo antagonist
13
Q
Benzo Side Effects
A
Drowsiness, anterograde amnesia, additive effects w/other CNS depressants, Dependance, tolerance
14
Q
Barbituate Side Effects
A
Toxicity can lead to coma and death
Classic inducer of P450
15
Q
The Z drugs
A
Zolpidem, Zaleplon, Eszopiclone
Nonbenzo hypnotics for sleepiness
