Insecticides: Crossword Questions Flashcards

1
Q

Specific carbamate for which 2-PAM is contraindicated

A

Carbaryl

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2
Q

Naphthalene causes this type of damage to RBCs

A

oxidative

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3
Q

Stimulation of this by nicotine can cause self-decontamination

A

CRTZ

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4
Q

IV _______ therapy is sometimes used to treat highly

lipophilic toxins

A

lipid

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5
Q

Piscicide that targets cellular metabolism

A

Rotenone

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6
Q

Rapid paralysis of insects by the action of pyrethrins

on neuronal sodium channels

A

Knockdown

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7
Q

Acidification of urine can _______ excretion of Nicotine

A

increase

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8
Q

Treats severe muscle tremors in pyrethrin toxicity

A

Methocarbamol

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9
Q

The half-life of Ivermectin is ______ than that of Amitraz

A

longer

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10
Q

Specific antagonist for Amitraz toxicity

A

Atipamazole

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11
Q

Dose repeatedly with ______________

if a toxin is known to undergo enterohepatic recycling

A

Activated charcoal

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12
Q

Where most Ivermectin is excreted intact

A

feces

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13
Q

This happens to organochlorines in fat animals

A

redistribution

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14
Q

Protein responsible for keeping Ivermectin out of the CNS

A

P-glycoprotein

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15
Q

Suspected to be part of D-Limonene’s mechanism of action

A

Hypotension

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16
Q

Contraindicated if significant CNS depression or seizures

present

A

Emesis

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17
Q

Organophosphate bond to Ach-esterase,

different from Carbamates

A

irreversible

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18
Q

Toxin with a very rapid onset that can

be enhanced by concurrent antacid therapy

A

Nicotine

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19
Q

Onset and duration of Carbamate toxicity is

usually ________ than Organophosphate

A

faster

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20
Q

Naphthalene mothballs do this in water

A

Float

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21
Q

Used in treatment of both organophosphate and carbamate toxicity

A

Atropine

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22
Q

Channels that organochlorines target

A

sodium-channels

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23
Q

Most sensitive to pyrethrins

A

Fish

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24
Q

Inhibitory neurotransmitter that accounts for some of

the toxicity with Ivermectin

A

GABA

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25
CNS _________ is a common presenting sign of Amitraz toxicity
CNS _depression_
26
Perhaps the most prominent sign of pyrethrin toxicity
Tremors
27
Can occur during aggressive treatment of pyrethrin toxicity and it can prolong clinical signs
hypothermia
28
Very high lipophilicity of DDT has lead to this in the food chain
Bioaccumulation
29
Organochlorine toxicity usually causes \_\_\_\_\_\_\_\_\_ of the CNS
Stimulation
30
Clinically found in cats with Naphthalene toxicity
Methemoglobin
31
Nicotine, organophosphates, and carbamates all mimic exaggerated amounts of this neurotransmitter
Acetylcholine
32
Free hemoglobin poses a risk of damage to these
Kidneys
33
These pyrethroids are more potent insecticides because of their alpha-cyano group
Type 2
34
Can greatly enhance absorption of Rotenone
oils
35
Increases the skin absorption of some pyrethroids (like Fenvalerate)
DEET
36
A common feature of organochlorine toxicosis
seizures
37
Pyrethrins and pyrethroids are relatively \_\_\_\_\_\_\_\_ in air and light
unstable
38
Rotenone metabolites in mammals are this, different from fish and insects
nontoxic
39
Presence of organochlorine residues in this tissue confirms exposure but NOT toxicity
Fat
40
With organophosphates, this kind of polyneuropathy is sometimes seen
delayed
41
Flower extract that can be used as an insecticide
pyrethrum
42
The receptors first affected by Ach-esterase inhibitors
muscarinic
43
With nicotine toxicity, a _______ urine pH will reduce excretion
high
44
D-limonene is frequently used in shampoos that repel or treat this parasite
flea
45
Fenthion is an example of an organophosphate that requires this for toxicity
bioactivation
46
Dichlorvos is unique among organophosphates in that it can do this in fat
sequester
47
Late stages and ultimate death with OP and Carbamate toxicity results from this occurring at nicotinic receptors
blockade
48
Toxic Epidermal Necrolysis has rarely been reported with this product
D-limonene
49
If a cat presents with acute toxicity consisting of CNS depression, hypotension, and a wet oily spot on their back, you may not be surprised if the spot smells like this
Citrus
50
An RBC morphology that indicates oxidative stress and can be seen in Naphthalene toxicity
Heinz Body
51
Generally more toxic by inhalation than by ingestion
Rotenone
52
Piperonyl butoxide is often added to pyrethroids to do this to their metabolism
slow
53
Most sensitive to organochlorine toxicity
Cat
54
An excitatory neurotoxin in dogs and cats for which the mechanism of action has not been determined
DEET
55
Organophosphates may undergo storage \_\_\_\_\_\_\_\_\_\_\_ but Carbamates do not
activation
56
Onset of signs after toxic nicotine exposure
rapid
57
P-glycoprotein acts as this type of pump to keep Ivermectin out of the CNS
efflux
58
Sometimes seen in Amitraz toxicity due to the toxin's effects on insulin
hyperglycemia
59
Inappropriate use of canine products on felines is a common cause for this toxicity
pyrethroid
60
Slowing Na+ efflux and K+ influx leading to partial depolarization of nerves is the main mechanism of action of what toxin group?
Organochlorine
61
Enterohepatic recycling is significant in organochlorine toxicity because of this feature of the toxin
lipophilicity
62
Carbamate bond to Ach-esterase, which is part of the reason 2-PAM is less effective
reversible
63
Unlike OP toxicity in other animals, in ruminants, you may see CNS \_\_\_\_\_\_\_\_\_
depression
64
A more potent way to be exposed to rotenone
inhalation
65
A metabolite of DDT is o,p-DDD (Mitotane) which can affect this gland
Adrenal
66
Functional adaptation and receptor downregulation can account for this, seen in some chronic OP exposures
tolerance
67
Decontamination therapy for D-Limonene exposure will usually involve this
bathing
68
Has a very long half life (YEARS) in soil
DDT
69
OPs that require lethal synthesis are generally _____ toxic to very young animals
less
70
Minimum # of mothballs that could cause toxicity to a 6.5 kg dog if ingested
ONE