Innate Immunity Flashcards

1
Q

What is your third line defense

A

Adaptive immunity

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2
Q

Summarize what innate immunity does

A

Lowers the number of pathogens

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3
Q

Does the immune system react to foreign invaders

A

Yes

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4
Q

Define cytokines

A

Communication chemicals that promote immune functions

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5
Q

What is the initial immediate defense against foreign invader that is present at birth

A

Innate immunity

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6
Q

Does innate immunity have the same responses regardless of Invader and regardless of number of exposures

A

Yes

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7
Q

What is the barrier first-line defense placed at surfaces that’s non-specific

A

Skin

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8
Q

Define nonspecific

A

It doesn’t care who the invader is it will kick it out

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9
Q

If breach first line defenses what does the second line defense do

A

They react to pathogen associated molecular pattern (PAMPs) using pattern recognition receptors on sentinel cells

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10
Q

What is an example of a Second line defense

A

Phagocytes they have receptors that look for any foreign patterns

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11
Q

What are the components of the first line defenses

A

Skin and mucous membranes

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12
Q

What are the components of the second line defenses

A

Leukocytes. Protein substances. Inflammation. Fever

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13
Q

What are the physical barriers of the skin and mucous membranes

A

Skin and mucous membranes and mucus

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14
Q

What are the flushing actions of the first line defenses

A

Sweat. Tearing. Peristalsis. Vomiting and diarrhea. Coughing and sneezing. Etc.

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15
Q

What are some of the chemical factors of the first line defenses and their examples

A

Salt. Acids ex. Stomach, urinary, vagina. Enzymes ex. In your mouth, tears, mucus. Other ex. They find a foreign invader find a ring structure and lyse it.

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16
Q

Does the normal flora help with the second line defense

A

No. The first-line defense

17
Q

What is the outcome of the first line defenses

A

Strategically placed to present invasion of deeper tissues

18
Q

What is your first and second line defenses

A

Innate immunity

19
Q

Describe A fever

A

A normal BT would be 37°C (hypothalamus regulated)

In an infection, cytokines called pyrogens released by macrophages

20
Q

What do pyrogens stimulate in the fever

A

Release of prostaglandins in the brain which set “ Thermo stat” higher

21
Q

What are the outcomes of a fever

A

Microbes inhibited and body defenses accelerated