Humoral Immunity; Adaptive Immunity

Question 1

Describe what happens in step two of humoral immunity

Answer 1

Specific helper T cells binds MHC – Ag complex via T cell receptor (TCR)
APC secrete cytokines
Clonal expansion and differentiation of helper T cell into TH cells and memory helper T cells

Question 2

Describe what happens in step three of humoral immunity

Answer 2

Specific B cell binds antigen via B cell receptor (BCR)
TH cell secretes cytokines to B cell
Clonal expansion and differentiation of B cells into plasma cells in memory B cells
Plasma cells make antibodies
Outcome is antibodies destroy extracellular pathogen’s

Question 3

What is the structure of antibodies

Answer 3

Constant and variable regions

Question 4

Where are the Ag binding sites

Answer 4

On the tip of variable sites ; they have 2 Ag binding sites

Question 5

Antibodies work via how many mechanisms

Answer 5

6

Question 6

Describe what happens in step one of humoral immunity

Answer 6

Antigens filtered out and binds antigen presenting cell (APC)
APC degrades into Jean into peptide fragments with your presence on its surface in MHC (major histocompatibility) molecules
APC migrates from tissues to lymphoid organs presenting antigens