Inflammation; Innate Immunity - Second Line Defenses

Question 1

What are the pro inflammatory mediators released by damage cells and macrophages

Answer 1

Histamine. Prostaglandins. Leukotrienes

Question 2

Describe Vasodilation

Answer 2

Dilating the blood vessels (Redness, heat)

Question 3

Describe increase vascular permeability

Answer 3

Becomes leaky and stuff leaks out into surrounding tissues (swelling, pain)

Question 4

Describe phagocyte diapedesis

Answer 4

Phagocytose squeeze out of your blood vessels : neutrophils –> monocytes to macrophages

Question 5

Describe phagocyte and microbial death

Answer 5

Pus (dead cells and abscess)

Question 6

What are the outcomes of inflammation

Answer 6

Destroys agent, localizes response, restores function

Question 7

Will you be OK if you had a systemwide inflammation

Answer 7

No it can kill you

Question 8

Would these same responses be beneficial if they were chronic

Answer 8

No phagocytosis can be destructive, they can spray the area with enzymes to Invader, it would promote damage and inflammation

Question 9

Describe inflammation

Answer 9

Heat, swelling, pain, redness and is Triggered by microbes, complement and tissue damage