Innate Immunity Flashcards

1
Q

Innate Immuntiy DEF

A

Defenses we are born with that consists of immune mechanisms that are hard wired to recognize and neutralize a broad range of threats.

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2
Q

Innate Immunity (characteristics)

A

Consists of 2 lines of defenses that Do not function to allow specific recognition of invaders and pathogens as it also lacks memory component to fight off previous invaders.

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3
Q

Innate Immunity’s First Line of Defense is Composed of 2 types of barriers and Microbiota.

A

Physical BArriers- Epidermis acts as a tough protective barrier, & Mucous membranes line the respiratory, gastrointestinal, and urogenital tracts.
CHEMICHAL BARRIERS- Secretions such as mucus, saliva, tears, and (stomach) hydrochloric acid aid in neutralization and eradication of pathogens.
MICROBIOTA- Commensal bacteria on the skin and mucous membranes compete with potential pathogens and produce substances that inhibit their growth.

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4
Q

Second Line of Defense is composed of

A

Internal mechanisms and cells that respond to pathogens in the forms of:
-Inflammation which (increases blood flow and wbc accumulation at the site of the infection,
-fever, which( inhibits pathogen growth
CELLS- being
Phagocytes- which engulf and digest pathogens
Natural Killer cells- that target and destroy infected cancerous cells
Dendritic cells- cells that process antigens and present them to T cells, linking innate and adaptive immunity

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