Innate Host Resistance Flashcards
What is susceptibility?
Lack of resistance to a disease.
What is immunity?
Ability to ward off disease.
What is the immune system?
Recognizes foreign substances or microbes and acts to neutralize or destroy them.
What is innate immunity?
Defenses against any pathogen.
What is adaptive immunity?
Immunity or resistance to a specific pathogen.
What is the first line of defense in innate immunity?
- intact skin
- mucous membranes and their secretions
- normal microbiota
What is involved in the second line of defense of the innate immunity?
- phagocytes, such as neutrophils, eosinophils, dendritic cells, and macrophages
- inflammation
- fever
- antimicrobial substances
What is involved in the third line of defense in adaptive immunity?
- specialized lymphocytes: T cells and B cells
- antibodies
What is the first line of defense against microbes?
Barriers
What is the effectiveness of physical barriers in nonspecific (innate) resistance impacted by?
- direct factors
> nutrition, physiology, fever, age, and genetics - indirect factors
> personal hygiene, socioeconomic status, and living conditions