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Phar 504 > Innate and Adaptive immunity > Flashcards

Innate and Adaptive immunity Flashcards

1
Q

Intracellular killing by phagocytes

A

Adhesion to pathogen, phagocytosis of who cells or viral particles with passage to endosomes and lysosomes

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2
Q

Extracellular killing

A

toxic metabolites, pore formation, induction of apoptosis

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3
Q

Endocytosis

A

nonspecific pinocytosis or specific receptor mediated uptake, fusion with endosomes then with lysosomes containing degradative enzymes (intracellular killing)`

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4
Q

Polymorphonuclear (PMN) leukocytes

A

eosinophils, basophils,neutrophils/ short lived

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5
Q

Natural Killer cells

A

early responders to virus-infected or cancer cells, attack if there is a lack of MHC 1

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Phar 504 (34 decks)

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