hybridomas and Monoclonal antibodies Flashcards

1
Q

polyclonal antibodies

A

complex mixtures by a single animal host, not reproducible from one host to another, different affinity and epitope specificity

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2
Q

T/F: Polyclonal antibodies are more likley to exhibit cross reactivity with interfering substances

A

True

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3
Q

What is taken from the mouse to help create hybridomas

A

splenocytes

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4
Q

What gene allows for HAT medium to select for cells that will be used

A

HGPRT+

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5
Q

T/F: Monoclonal antibodies are are only one type

A

True

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6
Q

T/F: It is easy to make monoclonal antibodeis against antigents that the host is tolerant to

A

False: it is quite difficult and almost impossible

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7
Q

How many epitopes can a monoclonal antibody recognize

A

1

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8
Q

biosimilar

A

biopharmaceutical product that is almost an identical copy of an original product that is manufactured by a different company

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