hybridomas and Monoclonal antibodies Flashcards
polyclonal antibodies
complex mixtures by a single animal host, not reproducible from one host to another, different affinity and epitope specificity
T/F: Polyclonal antibodies are more likley to exhibit cross reactivity with interfering substances
True
What is taken from the mouse to help create hybridomas
splenocytes
What gene allows for HAT medium to select for cells that will be used
HGPRT+
T/F: Monoclonal antibodies are are only one type
True
T/F: It is easy to make monoclonal antibodeis against antigents that the host is tolerant to
False: it is quite difficult and almost impossible
How many epitopes can a monoclonal antibody recognize
1
biosimilar
biopharmaceutical product that is almost an identical copy of an original product that is manufactured by a different company