Injectable Anaesthetics: Barbiturates and Pentobarbitone Flashcards
1
Q
What do barbiturates cause?
A
- Adequate muscle relaxation
- Unconsciousness
2
Q
Do barbiturates provide good analgesic properties
A
NO
3
Q
Why do barbituates have a rapid onset of anaesthesia
A
Highly lipid soluble and so enter the brain tissue rapidly (15-30seconds)
4
Q
Where do barbituates redistribute?
A
blood levels fall as it goes into plasma and then redistributed into muscle/fat
5
Q
Name 3 patients that baributates are not suitable for?
A
- Renal / hepatic patients
- Patients with cardiovascular disease
- Shocked patients
- Thin patients
6
Q
Why are barbiturates not suitable for thin patients
A
increased potency due to lack of body fat to redistribute drug
7
Q
Why are barbiturates not suitable for shocked patients?
A
Reduced blood flow to fat and increased cardiac and cerebral blood flow
8
Q
Name a barbiturate anaesthetic drug
A
- thiopentone
- methohexitone
- pentobarbitone
9
Q
What two functions do pentobarbitone have?
A
- Anticonvulsant
- Humane destruction
