Inhibition of Enzyme activity

Question 1

Subs that can diminish the velocity of an enzyme catalyzed rxn

Answer 1

Inhibitor

Question 2

Types of inhibition

Answer 2

Competitive

Noncompetitive

Question 3

Factors affecting enzyme rxns

Answer 3

Substrate conc
Temp
pH

Question 4

Regulation of enzyme activity by

Answer 4

Allosteric regulation

Covalent modification

Question 5

HMG Coenzyme A inhibitor

Answer 5

Statins

Question 6

Lower serum lipid conc

Answer 6

Statins

Question 7

Inhibitor of viral reverse transcriptase

Answer 7

Emtrictabine

Tenofovir disoproxil fumarate

Question 8

Block replication of HIV

Answer 8

Emtrictabine

Tenofovir disoproxil fumarate

Question 9

Anti HTN agts

Answer 9

ACE inhibitors

Question 10

-Prils

Answer 10

ACE inhibitors

Question 11

Inihibitors of alanyl alanine carboxypeptidase-transpeptidase

Answer 11

Lactam antibiotics

Question 12

Block cell wall synthesis

Answer 12

Lactam antibiotics

Question 13

Penicillin

Amoxicillin

Answer 13

Lactam antibiotics

Question 14

Regulation of an enzyme or other protein by binding an effector molecule at the protein’s allosteric site.

Answer 14

Allosteric regulation

Question 15

A donor molecule provides a functional moiety that modifies the properties of the enzyme.

Answer 15

Covalent modification