Enzymes Flashcards
Inc rate of rxn
Enzyme
Reactant aka
Substrate
Regulated frm a state of low activity to high activity & vice versa
Enzymes
Most enzymes are
Proteins
Peptide component aka
Apoenzyme
Cofactor aka
Coenzyme
Combined functional unit aka
Holoenzyme
Cofactor is
Non-peptide component
Cofactors that are tightly bound to the polypeptide
Prosthetic groups
Proteins w/o prosthetic groups
Simple proteins
Prosthetic groups are
Complex/conjugated proteins
Inactive form of apoenzyme
Proenzyme/Zymogen
Proenzyme aka
Zymogen
Contain several amino acids in the protein w/c are removed & allows the final specific tertiary structure to be formed before it is activated as an apoenzyme
Proenzyme/Zymogen
Common coenzymes eg
Vitamins
Metal ions
Metal ions used in enzymes as cofactors
Zn Mg Mn Fe Cu K Na
Tightly incorporated into protein struct by covalent/ noncovalent forces
Prosthetic groups
Prosthetic groups eg
Deriv of Vit B
FMN
Flavin mononucleotide
FAD
Flavin adenine dinucleotide
Pyridoxal phosphate
Prosthetic groups
Thiamin pyrophosphate
Prosthetic groups
Biotin
Prosthetic groups
Metal ions Prosthetic groups
Co Cu Mg Mn Zn
Enzymes that contain tightly bound metal ions
Metalloenzymes
6 Major classes of enzymes
Oxidoreductase Hydrolases Isomerases Transferases Lyases Ligases
Breaks down starch
Amylase
Breaks down fibers
Cellulase
Breaks down dairy products
Lactase
Breaks down fats
Lipase
Breaks down grains
Maltase
Breaks down proteins
Protease
Breaks down sugars
Sucrase