Enzymes Flashcards
Inc rate of rxn
Enzyme
Reactant aka
Substrate
Regulated frm a state of low activity to high activity & vice versa
Enzymes
Most enzymes are
Proteins
Peptide component aka
Apoenzyme
Cofactor aka
Coenzyme
Combined functional unit aka
Holoenzyme
Cofactor is
Non-peptide component
Cofactors that are tightly bound to the polypeptide
Prosthetic groups
Proteins w/o prosthetic groups
Simple proteins
Prosthetic groups are
Complex/conjugated proteins
Inactive form of apoenzyme
Proenzyme/Zymogen
Proenzyme aka
Zymogen
Contain several amino acids in the protein w/c are removed & allows the final specific tertiary structure to be formed before it is activated as an apoenzyme
Proenzyme/Zymogen
Common coenzymes eg
Vitamins
Metal ions
Metal ions used in enzymes as cofactors
Zn Mg Mn Fe Cu K Na
Tightly incorporated into protein struct by covalent/ noncovalent forces
Prosthetic groups
Prosthetic groups eg
Deriv of Vit B
FMN
Flavin mononucleotide
FAD
Flavin adenine dinucleotide
Pyridoxal phosphate
Prosthetic groups
Thiamin pyrophosphate
Prosthetic groups
Biotin
Prosthetic groups
Metal ions Prosthetic groups
Co Cu Mg Mn Zn