Inherited Cardiomyopathies Flashcards
What are signs of hypertrophy
jerky pulse
forceful or double tap apex
fourth heart sound
midsystolic murmur exacerbated by valsava maneuvre
what are ECG changes that might be seen
increase voltage= hypertophy
st depression indicated LV strain
What is the most common cause of SCD in young people
hypertrophic cardiomyopathy
what is the most common type of hypertrophy
septal
What murmur can arise from hypertrophy
mitral regurg
heart murmur similar to aortic stenosis may arise
what do symptoms of hypertrophy mimic
CHF but are made worse on diuretic
What are the risks in hypertrophy
progressive HF and AF
What type of inheritance is hypertrophic cardiomyopathy
autosommal dominant
Where are the mutated genes in hypertrophic cardiomyopathy
mutations in sarcometric genes and mitochondrial DNA
What is the treatment of hypertrophic cardiomyopathy
Ist =beta blocker
2nd -calcium channel blocker- verapamil
What happens in dilated cardiomyopathy
increased diastolic and sysolic volume but low ejection fraction
what type of inheritance is dilated cardiomyopthay
autosommal dominant
uncommonly recessive and x linked
where are the mutation is dilated cardiomyopathy
cytoskeletal proteins and nuclear transport proteins
What is the treatment for dilated
like heart failure- diuretci, ACE, betablocker, digoxin
how does arrhythmogenic right ventricular cardiomyopathy present
right sided heart problem eg RBBB
ECg changes
myocarditis
