Inheritance, Variation and Evolution Flashcards
What is deoxyribonucleic acid (DNA)?
The chemical a cell’s nuclear genetic material is made from
What are chromosomes?
Long molecules of DNA that normally come in pairs
Humans have 23 pairs.
The 23rd pair carries the genes which decide a person’s sex (XX or XY)
What is a gene?
A small section of DNA found on a chromosome.
Each gene codes for a particular sequence of amino acids, which are put together to make a specific protein
How many different amino acids are there and how many possible proteins?
20 amino acids
1000s of proteins
What is a genome?
An organism’s entire set of genetic material
What 2 things can we do now that we have worked out the entire human genome?
1: genes linked to diseases can be identified - this helps us better understand inherited diseases, so we can develop effective treatments
2: tiny differences in people’s genomes can be studied - this helps us trace migration patterns of past human populations
What 2 things make up a nucleotide?
A sugar-phosphate backbone and one of the 4 bases
What are the two complementary base pairs?
A + T
G + C
How many bases code for 1 amino acid?
3
Talk me through protein synthesis.
1: mRNA is copied from DNA template and moves to the ribosomes
2: proteins are synthesised on ribosomes
3: carrier molecule brings specific amino acid
4: they form a chain
What are mutations?
Changes to the sequence of DNA bases. They occur continuously
What effect do most mutations have?
No effect on the protein
What effect do some mutations have?
Alter the protein slightly but its shape and function are not affected
What effect do very few mutations have?
Change the shape of the protein and affect its function.
Eg, an enzyme substrate no longer fits or a structural protein loses its strength
Tell me about asexual reproduction.
One parent
Cell division by mitosis
Produces genetically identical offspring
Advantages:
Fast compared to sexual reproduction, so many identical offspring can be produced in favourable conditions
Tell me about sexual reproduction.
Two parents
Cells divide by meiosis and mitosis
Produces offspring containing a mixture of the parent’s genes
Advantages:
The variation produced in the offspring increases the chance that some individuals of a species will survive a change in the environment.
We can use selective breeding to utilise the variation in offspring and increase food production
Describe meiosis to me.
1: The cell duplicates its genetic information
2: The cell divided and each new cell had one copy of each chromosome
3: Both cells divide again to make 4 gametes
4: Each gamete only has a single set of chromosomes
What is an allele?
A version of a gene
What do we mean by dominant?
An allele that is always expressed
What do we mean by recessive?
An allele that is only expressed when 2 copies are present
What does homozygous mean?
Both of an organisms alleles for a trait are the same
What does heterozygous mean?
An organisms alleles for a trait are different
What is a genotype?
An organisms combination of alleles
What is a phenotype?
The characteristics an organism has (visible)