Inheritance Flashcards

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1
Q

Define genotype.

A

The genetic constitution of an organism.

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2
Q

Define phenotype.

A

The expression of an organism’s genetic constitution, combined with its interaction with the environment.

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3
Q

What is an allele?

A

Different forms of a particular gene, found at the same locus (position) on a chromosome.

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4
Q

How many alleles per gene do diploid organisms carry?

A

2

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5
Q

What is meant by a dominant allele?

A

An allele whose characteristic will always

appear in the phenotype, whether 1 or 2 are present.

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6
Q

What is meant by a recessive allele?

A

An allele whose characteristic only appears in the phenotype if no dominant allele is present, meaning 2 must be present.

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7
Q

What is meant by codominant alleles?

A

2 dominant alleles that both contribute to the phenotype, either by showing a blend of both characteristics, or the
characteristics appearing together.

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8
Q

What does homozygous mean?

A

both alleles are dominant,

or both alleles are recessive.

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9
Q

What does heterozygous mean?

A

1 allele is dominant, the other is recessive.

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10
Q

Define monohybrid inheritance.

A

Where 1 phenotypic characteristic is controlled by a single gene.

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11
Q

Define dihybrid inheritance.

A

Where 2 phenotypic characteristics are determined by 2 different genes present on 2 different chromosomes at the same time.

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12
Q

What is meant by sex-linkage?

A

Where an allele is located on one of the sex chromosomes, meaning its
expression depends on the sex of the individual.

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13
Q

Why are males more likely to express a recessive sex-linked allele?

A

Most sex-linked alleles are located on the X chromosome.
Therefore males only get 1 copy of the allele, so will express this characteristic even if it’s recessive.
Since females get 2 alleles, this is less likely.

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14
Q

Which parent do males inherit sex-linked characteristics from?

A

Their mother, since the Y chromosome can only come from their father. Therefore if the mother is heterozygous for sex-linked
alleles, she is a carrier and may pass on the trait on.

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15
Q

What is meant by autosomal linkage?

A

Where 2 or more genes are located on the same (non-sex) chromosome.
In this case, only 1 homologous pair is needed for all 4 alleles to be present.
For genes that aren’t linked, 2 homologous pairs are needed.

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16
Q

If IA and IB are codominant and IO is recessive, which

alleles could the offspring express?

A

AB, A, B, O

17
Q

What is meant by epistasis?

A

Where 2 non-linked genes interact, with one gene either masking or suppressing the other gene.

18
Q

What is recessive epistasis?

A

Where 2 homozygous recessive alleles mask

expression of another allele.

19
Q

What is dominant epistasis?

A

Where one dominant allele masks expression of multiple other alleles.

20
Q

What is the chi-squared test?

A

A statistical test to find out whether the difference between observed and expected data is due to chance or a real effect.

21
Q

What are the criteria for the chi-squared test?

A

● Data placed in discrete categories
● Large sample size
● Only raw count data allowed i.e. not percentages
● No data values equal zero

22
Q

How is a chi-squared test performed?

A

The formula results in a number, which is then
compared to a critical value. If the number is greater than or equal to the critical value, we conclude there is no significant difference and the results occured due to chance.

23
Q

How can we use a chi-squared test in relation to the content of this topic?

A

We can compare expected phenotypic ratios with observed ratios to test our
understanding of how different genes and alleles are inherited.