Inheritance (17) Flashcards

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1
Q

What is the genotype?

A

genetic construction of an organism

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2
Q

What is the phenotype?

A

expression of an organisms genetic constitution combined with its interaction with the environment

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3
Q

What is an allele?

A

different forms of a particular gene found at the same locus on a chromosome

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4
Q

How many alleles could a single gene have?

A

many

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5
Q

What is a diploid organism?

A

organism that carries 2 alleles per gene

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6
Q

What is a dominant allele?

A

allele whose characteristic will always appear in the phenotype, whether 1 or 2 are present

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7
Q

What is recessive allele?

A

allele whose characteristics only appears in the phenotype if no dominant allele is present

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8
Q

What are codominant alleles?

A

2 dominant alleles that both contribute to the phenotype, either by showing a blend of characteristics, or characteristics appearing together

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9
Q

What is meant by homozygous?

A

when both alleles dominant or both recessive

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10
Q

What is meant by heterozygous?

A

when one alleles is dominant and one recessive

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11
Q

What is meant by monohybrid inheritance?

A

when one phenotypic characteristic is controlled by a single gene

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12
Q

What 2 ratios does a monohybrid cross produce?

A

3:1
1:2:1 due to codominance

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13
Q

Is brown eyes phenotype, genotype, or gamete?

A

phenotype

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14
Q

Is Bb phenotype, genotype, or gamete?

A

genotype

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15
Q

Is B phenotype, genotype, or gamete?

A

gamete

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16
Q

What is meant by dihybrid inheritance?

A

where 2 phenotypic characteristics are determined by 2 different genes present on 2 different chromosomes at the same time

17
Q

What are the 4 ratios that can result from a dihybrid cross punnet square?

A

9:3:3:1
3:1 due to linkage
9:3:4 due to epistasis
12:3:1 due to epistasis

18
Q

What is sex-linkage?

A

where an allele is located on 1 of the sex chromosomes, meaning its expression depends on the individual’s sex

19
Q

Which chromosome is the sex chromosome?

A

23rd chromosome

20
Q

Why are males more likely to express recessive sex-linked allele?

A

most sex-linked alleles are located on the X chromosome, therefore males only get one copy of the allele, so will express this characteristics even if it’s recessive - females get 2 alleles so this is less likely

21
Q

Which parents do males inherit sex-linked characteristics from and why?

A

their mother since the Y chromosome can only come from their father, therefore if mother is heterozygous for sex-linked alleles - she is a carrier and may pass the trait on

22
Q

What is autosomal linkage?

A

where 2 or more genes are located on the same non-sex chromosome

23
Q

Which are the non-sex chromosomes?

A

the first 22 chromosomes

24
Q

What is epistasis?

A

where 2 non-linked genes interact, with one gene either masking or suppressing the other gene

25
Q

What are the 2 types of epistasis?

A

recessive epistasis
dominant epistasis

26
Q

What is recessive epistasis?

A

where 2 homozygous recessive alleles mask the expression of another allele

27
Q

What is dominant epistasis?

A

where 1 dominant allele masks the expression of multiple other alleles

28
Q

What is the chi-squared test?

A

statistical test to find out whether the difference between observed and expected data is due to chance or a real effect

29
Q

What are the 4 criteria for chi-squared test?

A
  • categorical data
  • large sample
  • only raw count data allowed (e.g. not percentages)
  • no data values = 0
30
Q

What are the 2 steps in performing a chi-squared test?

A

1) formula results in a number
2) compare number to critical value for the corresponding degree of freedom

31
Q

If the p is less than or equal to 0.05, what does this mean?

A

significant difference
not due to chance
reject null hypothesis

32
Q

If the p is more than 0.05, what does this mean?

A

no significant difference
due to chance
accept null hypothesis

33
Q

How can the chi-squared test be used for investigating inheritance?

A

we can compare expected ratios with observed ratios to test our understanding of how different genes and alleles are inherited