Inhalant Anesthetics Flashcards
The lower the solubility, the _____ onset and recovery
faster
Which anesthetic agent has the lowest solubility?
Desflurane
Isoflurane (1.4) > sevoflurane (0.68) > desflourane (0.45)
What happens to vapor pressure as temperature DECREASES?
Decreases
The dose required to reach a desired effect
potency
measured in minimum alveolar concentration (MAC)
MAC of isoflurane
1.2%
MAC of sevoflurane
2.2%
MAC of desflurane
7-8%
MAC of desflurane
7-8%
When is NO usually used?
Concurrently with other agents to lower their MAC
Factors affecting MAC
Increase MAC: hyperthermia, hypernatremia, drugs that cause CNS stimulation, increased levels of excitatory NTs
Decreased MAC: other anesthetics, hyponatremia, hypotension, hypothermia, low O2, high CO2, pregnancy, age
Factors affecting MAC
Increase MAC: hyperthermia, hypernatremia, drugs that cause CNS stimulation, increased levels of excitatory NTs
Decreased MAC: other anesthetics, hyponatremia, hypotension, hypothermia, low O2, high CO2, pregnancy, age
3 factors that influence uptake
- solubility of anesthetic
- patients cardiac output
- alveolar-venous anesthetic partial pressure difference
Cardiac output
Increase CO = greater amount of blood carrying inhalant away from alveoli to tissue
Decreased CO = less anesthetic removed
Inhalants ______ cerebral blood flow
increase
they can increase intracranial pressure
Inhalants ______ cardiac output
reduce
