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Pharm Exam 3 > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Beta-Lactams

A

Penicillins: Penicillin G, Aminopenicillins (Amoxicillin)
Extended spectrum penicillins (ticarcillin)

Cephalosporins

Others: carbapenem, Imipenem, Beta-lactamse inhibitors (Clavulanic acid)

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2
Q

Aminoglycosides

A

Gentamycin

amikacin

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3
Q

Phenicols

A

Chloramphenicol (SA)

Florphenicol (LA)

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4
Q

Lincosamides

A

Lincomycin

Clindamycin

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5
Q

Tetracyclines

A

Oxytetracyclin

Doxycyclin

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6
Q

Fluoroquinolones

A

Enrofloxacin

Marbofloxacin

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7
Q

Macrolides

A

Azithromycin

Tylosin

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8
Q

Polypeptides

A

Vancomycin
Bacitracin
Polymixin

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9
Q

Potentiated sulfonamides

A

sulfas + trimethoprim

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10
Q

Miscellaneous antibiotics

A

Rifampin (horses)

Metronidazole

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11
Q

Cell wall synthesis inhibitors

A

Penicillin (Beta lactams)
Cephalosporin (Beta lactams)
Vancomycin (polypeptide)

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12
Q

Inhibition of Protein synthesis (30s or 50s)

A

Chloramphenicol
Tetracyclin
Clindamycin

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13
Q

Cell Membrane Leakage

A

Polymixin
Nystatin
Amphotericin B

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14
Q

Inhibition of protein synthesis (30s) aminoglycosides

A

Gentamicin

Amikacin

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15
Q

Affect nucleic acid metabolism

A

Rifampin

Enrofloxacin

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16
Q

Anti-metabolites

A

Trimethoprim

Sulfonamides

17
Q

Antibiotics that are concentration dependent

A

Quinolones
Aminoglycosides
Metronidazole

18
Q

Antibiotics that are time-dependent (no persistent effects)

A

Beta lactams

19
Q

Antibiotics that are time-dependent (with persistent effects)

A

Macrolides
Tetracyclines
Lincosamides

20
Q

What is the most important mechanism of antibiotics resistance?

A

Plasmid

21
Q

How to slow resistance process

A

Judicious use
Culture and sensitivity
Correct dose, frequency, and route
Avoid using the newest antibiotic

22
Q

What antibiotics target cell wall?

A

Penicillins
Cephalosporins
Carbapenems

23
Q

What antibiotics target ribosome 30s?

A

Aminoglycosides

Tetracyclines

24
Q

What antibiotics target ribosome 50s?

A

Macrolides
Phenicols
Lincosamides

25
Q

What antibiotics target purine metabolism?

A

Sulfonamides

26
Q

What antibiotics target DNA?

A

Fluoroquinolones
Nitrofurans
Rifampins

27
Q

Penicillins

A

Amoxicillin
Penicillin G
Ticarcillin

28
Q

First generation Cephalosporins

A 
cefazolin
cephalexin (dogs)
29
Q

Second generation cephalosporins

A

none used at uf

30
Q

Third generation cephalosporins

A

Cefotaxime

Ceftiofur (SA and LA)

31
Q

What are the major toxicities of aminoglycosides?

A

Nephrotoxicity
Ototoxicity
Neurotoxicity

32
Q

How do tetracyclines work?

A

Bacteriostatic - reversible inhibition of 30s

33
Q

What drug MUST be followed with water in cats?

A

Doxycycline

34
Q

What antibiotics are bacteriostatic with inhibition of 50s?

A

Phenicols
Macrolides
Lincosamides

35
Q

Antibiotics that penetrate CNS

A

Chloramphenicol
Doxycycline
Metronidazole
Some 3rd gen cephalosporins

Pharm Exam 3 (6 decks)

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