Info for Histopath

Question 1

Coagulative necrosis in striated muscle?

Answer 1

Zenker’s necrosis

Question 2

Name 2 things coagulative necrosis suggests (i.e. two causes)

Answer 2

hypoxia

ischemia

Question 3

Caseous necrosis is often associated with what?

Answer 3

poorly degradable lipids from bacterial membranes

Question 4

Classic cause of caseous necrosis?

Answer 4

tuberculosis

Question 5

Macrophages of the brain?

Answer 5

Gitter cells

Question 6

How can liquefactive necrosis occur in non-CNS tissues?

Answer 6

enzymes released by leukocytes destroy the pathogen and surrounding tissue

Question 7

3 types of fat necrosis

Answer 7

enzymatic, traumatic, idiopathic

Question 8

Special stains for:

1) hemosiderin
2) Amyloid

Answer 8

1) Prussian blue

2) Congo red

Question 9

Name 2 diseases that might cause accumulation of glycogen?

Answer 9

Diabetes mellitus

Hyperadrenocorticism

Question 10

______ is inhaled carbon present in the lungs

Answer 10

Anthracosis

Question 11

Why couldn’t you find a melanocytoma in the lungs?

Answer 11

Because they are benign and don’t metastasize

Question 12

Two sources of hematin?

Answer 12

1) formalin-related

2) parasite excreta (fluke puke!)

Question 13

Give two possible causes for post-hepatic cholestasis?

Answer 13

Choleliths, tumors, fibrosis

Question 14

5 cardinal signs of inflammation?

Answer 14

Redness
Swelling
Heat
Pain
Loss of function

Question 15

1) inflammation of the hair follicles

2) follicular rupture

Answer 15

1) folliculitis

2) furunculosis

Question 16

What special stain can be used for mast cells?

Answer 16

Toluidine blue

Question 17

Causative agent of woody tongue

Answer 17

Actinobacillus lignieresii

Question 18

Name 3 reasons hemorrhage can occur

Answer 18

1) endothelium/blood veseel integrity is compromised
2) platelet malfunction
3) coagulation factor malfunction

Question 19

Classic determinants of thrombosis (3)

Answer 19

1) endothelial injury
2) abnormal blood flow
3) hypercoagulability