Influenza Viruses Flashcards
1
Q
Life cycle of a virus
A
- Infection of host cell
- Replication
- Control host machinery and intracellular parasites
2
Q
Smallest virus and biggest virus
what’s the size range ?
A
Parvovirus an Ebolavirus
20 - 400 nm
3
Q
what’s a nucleocapsid ?
A
Capsid + genome
4
Q
Is it better to have naked or enveloped viruses?
A
Naked - more resistant to outside environment
Enveloped -less resistant
= influence ways virus are transmitted
5
Q
Virus morphologies
A
Polyhedral , helical , spherical , filamentous, complex
6
Q
The most deadliest flu pandemics?
A
- Spanish flu - 1918- 50 million
- Hong Kong flu- 1968 - 3 million
- Swine flu 105000-395000
7
Q
What’s an antigenic drift?
A
Small mutations affecting H and N antigens
8
Q
What’s antigenic shift ?
A
Less common, only influenza A–> Major mutation or shift in antigenicity of H or N ( recombination of diff viral genome in the same cell)
9
Q
what are the inactivated influenza vaccines?
A
Whole virus , split vaccine , subunit
